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Blood Coagulation Disorders Among the Iranian Population: a Systematic Review [PDF]
, 2023 Background: Blood coagulation disorders are one of the causes of mortality. Therefore, the study of coagulation disorders is also important. This systematic review was conducted to investigate blood coagulation disorders in the Iranian population ...
Fatemeh Mezginejad +9 more
core +1 more source
Modeling Disorders of Blood Coagulation in the Zebrafish [PDF]
Current Pathobiology Reports, 2015 Hemostasis, the process of blood clot formation and resolution in response to vascular injury, and thrombosis, the dysregulation of hemostasis leading to pathological clot formation, are widely studied. However, the genetic variability in hemostatic and thrombotic disorders is incompletely understood, suggesting that novel mediators have yet to be ...
Colin A, Kretz +2 more
openaire +2 more sources
The International Prospective Glanzmann Thrombasthenia Registry: Pediatric Treatment and Outcomes
TH Open, 2019 Background Standard treatment for Glanzmann thrombasthenia (GT), a severe inherited bleeding disorder, is platelet transfusion. Recombinant activated factor VII (rFVIIa) is reported to be effective in GT with platelet antibodies and/or refractoriness to ...
Rainer B. Zotz +3 more
doaj +1 more source
MODERN ASPECTS OF COAGULOPATHY DEVELOPMENT IN PATIENTS WITH COVID-19 INFECTION: LITERATURE REVIEW
Проблеми екології та медицини, 2021 This review summarizes current knowledge about coagulation disorders associated with COVID-19 infection. Despite a significant amount of research, it is currently unclear whether COVID-19 is the direct cause of coagulopathic disorders or they occur as ...
M.O. Dudchenko +2 more
doaj +1 more source
Laboratory Evaluation Of Patients With Undiagnosed Bleeding Disorders [PDF]
, 2016 The evaluation of patients with a bleeding tendency represents a challenge as the routinely available tests for evaluating bleeding disorders are limited, complicating the laboratory determination of the clinically observed bleeding tendency. As a result,
Santiago-Bassora, Fernanda Dutra +6 more
core +3 more sources
Acta Obstetricia et Gynecologica Scandinavica, 2022 Introduction Contraceptives containing ethinylestradiol (EE) induce changes in the coagulation system and are associated with a risk of venous thromboembolism.
Annina H. Haverinen +9 more
doaj +1 more source
Patient-Specific Modelling of Blood Coagulation [PDF]
, 2021 Blood coagulation represents one of the most studied processes in biomedical modelling. However, clinical applications of this modelling remain limited because of the complexity of this process and because of large inter-patient variation of the ...
Nechipurenko D. +7 more
core +3 more sources
BMC Research Notes, 2021 Objective Hospital data are a useful resource for studying pregnancy complications, including bleeding-related conditions, however, the reliability of these data is unclear.
Heather J. Baldwin +5 more
doaj +1 more source
Duplication of the prothrombin gene is associated with a significant increase in thrombin generation
Research and Practice in Thrombosis and HaemostasisBackground: Prothrombin gene mutations can be associated with either a thrombotic or a bleeding risk. Genomic studies and coagulation workup can provide valuable information to better understand their clinical importance.
Annelie Siegemund +6 more
doaj +1 more source
Platelet aggregation impacts thrombin generation assessed by calibrated automated thrombography
Platelets, 2018 A calibrated automated thrombogram (CAT) is performed usually with human platelet-free plasma (PFP) but may be more relevant with platelet-rich plasma (PRP). In this case, platelets are not stimulated by subendothelial molecules like collagen.
Mélusine Didelot +5 more
doaj +1 more source