Results 21 to 30 of about 189,627 (209)

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

open access: yes, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo   +6 more
core   +1 more source

Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A. [PDF]

open access: yes, 2012
nefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production.
Abriss, Daniela   +9 more
core   +9 more sources

The International Prospective Glanzmann Thrombasthenia Registry: Pediatric Treatment and Outcomes

open access: yesTH Open, 2019
Background Standard treatment for Glanzmann thrombasthenia (GT), a severe inherited bleeding disorder, is platelet transfusion. Recombinant activated factor VII (rFVIIa) is reported to be effective in GT with platelet antibodies and/or refractoriness to ...
Rainer B. Zotz   +3 more
doaj   +1 more source

Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]

open access: yes, 2016
The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
core   +2 more sources

Climacteric Lowers Plasma Levels of Platelet-Derived Microparticles: A Pilot Study in Pre-versus Postmenopausal Women [PDF]

open access: yes, 2012
Background: Climacteric increases the risk of thrombotic events by alteration of plasmatic coagulation. Up to now, less is known about changes in platelet-(PMP) and endothelial cell-derived microparticles (EMP). Methods: In this prospective study, plasma
Andreas Rank   +43 more
core   +3 more sources

MODERN ASPECTS OF COAGULOPATHY DEVELOPMENT IN PATIENTS WITH COVID-19 INFECTION: LITERATURE REVIEW

open access: yesПроблеми екології та медицини, 2021
This review summarizes current knowledge about coagulation disorders associated with COVID-19 infection. Despite a significant amount of research, it is currently unclear whether COVID-19 is the direct cause of coagulopathic disorders or they occur as ...
M.O. Dudchenko   +2 more
doaj   +1 more source

Human parvovirus B19 and blood product safety. A tale of twenty years of improvements [PDF]

open access: yes, 2015
Parvovirus B19 (B19V), long known to be the causative agent of erythema infectiosum (fifth disease), is not a newly emerging agent. The aim of this review is to analyse the role played by this virus in compromising safety in transfusion medicine and the ...
Calizzani, Gabriele   +7 more
core   +1 more source

From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]

open access: yes, 2015
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core   +2 more sources

Guidelines on fibrinogen assays [PDF]

open access: yes, 2003
No abstract ...
Becker   +52 more
core   +1 more source

Inherited disorders of blood coagulation

open access: yesAnnals of Medicine, 2011
Hemostasis is traditionally defined as a physiological response to blood vessel injury and bleeding, which entails a co-ordinated process involving the blood vessel, platelets, and blood clotting proteins (i.e. coagulation factors). Hemostasis can be divided into primary and secondary components.
LIPPI, Giuseppe   +3 more
openaire   +2 more sources

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