Results 21 to 30 of about 123,153 (305)

Management of a Patient with Bombay Blood Group and Chronic Liver Disease with Subdural Hematoma

Journal of Neuroanaesthesiology and Critical Care, 2022
The Bombay blood group is an extremely rare entity within the conventional ABO blood grouping system. End-stage liver disease also presents with myriad disorders of coagulation due to impaired synthesis and dysfunction of clotting factors, which ...
Siddharth Chavali, Subodh Raju, Suresh Kanasani, Abhirama C. Gabbita   +3 more
doaj   +1 more source

Blood Coagulation Disorders Among the Iranian Population: a Systematic Review

, 2023
Background: Blood coagulation disorders are one of the causes of mortality. Therefore, the study of coagulation disorders is also important. This systematic review was conducted to investigate blood coagulation disorders in the Iranian population ...
Fatemeh Mezginejad, Hassan Boustani, Abbasian, S., Mahnoosh Dibavar, Sadegh Abbasian, Negin Shokrgozar, Boustani, H., Dibavar, M. A., Mezginejad, F., Shokrgozar, N.   +9 more
core   +1 more source

Updated concepts on the pathophysiology and the clinical management of trauma hemorrhage and coagulopathy

Chinese Journal of Traumatology, 2017
Uncontrolled hemorrhage and subsequent trauma-induced coagulopathy (TIC) are still the principle causes for preventable death after trauma and early detection and aggressive management have been associated with reduced mortality.
Marc Maegele, Zheng-Tao Gu, Qiao-Bing Huang, Hong Yang   +3 more
doaj   +1 more source

COVID-19-associated coagulopathy in children and adolescents

Acta Biomedica Scientifica, 2021
The pandemic of the new coronavirus infection COVID-19 in 2020 has become the main health problem across the globe. A special characteristic of the SARSCoV-2 virus is tropism to the vascular endothelium with the  development of endotheliitis, which ...
M. V. Gomellya, A. V. Tatarinova, T. S. Krupskaya, L. V. Rychkova   +3 more
doaj   +1 more source

What role do coagulation disorders play in the pathogenesis of leptospirosis? [PDF]

, 2007
Leptospirosis is a zoonosis of worldwide distribution, spread by the urine of infected animals. It is a major public health problem, especially in developing countries, where circumstances for transmission are most favourable. The clinical picture varies
de Kruif, MD, ten Cate, H, Hartskeerl, Rudy A., Brandjes, DPM, Sakundarno, Mateus, Gasem, M. Hussein, Mairuhu, ATA, Wagenaar, Jiri F.P., van Gorp, Eric C. M., Goris, Marga G.A.   +9 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

It Is Written in the Clot: Coagulation Assessment in Severe Burn Injury

European Burn Journal
Background: Coagulopathy in severe burn injury is associated with complications and mortality. Methods: We compared 3 tests (EXTEM, INTEM, FIBTEM) of rotational thromboelastometry (ROTEM), a viscoelastic coagulation assay (VCA), with conventional ...
Eirini Nikolaidou, Andriana Lazaridou, Christina Iasonidou, Alexandra Tsaroucha, Sophia Papadopoulou, Eleni Kaldoudi, Apostolos Sovatzidis, Despoina Kakagia   +7 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Measurement of factor XIII for the diagnosis and management of deficiencies: insights from a retrospective review of 10 years of data on consecutive samples and patients

Research and Practice in Thrombosis and Haemostasis
Background: Factor XIII (FXIII) deficiency is a challenge in the diagnosis of rare bleeding disorders with inherited and acquired causes. Objectives: We evaluated consecutive cases tested for FXIII deficiency for insights on diagnosis.
Mohammed Abdullah Al Sharif, Natalie Mathews, Subia Tasneem, Karen A. Moffat, Stephen A. Carlino, Siraj Mithoowani, Catherine P.M. Hayward   +6 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source