Results 31 to 40 of about 3,484,780 (294)
Duplication of the prothrombin gene is associated with a significant increase in thrombin generation
Research and Practice in Thrombosis and HaemostasisBackground: Prothrombin gene mutations can be associated with either a thrombotic or a bleeding risk. Genomic studies and coagulation workup can provide valuable information to better understand their clinical importance.
Annelie Siegemund +6 more
doaj +1 more source
Platelet aggregation impacts thrombin generation assessed by calibrated automated thrombography
Platelets, 2018 A calibrated automated thrombogram (CAT) is performed usually with human platelet-free plasma (PFP) but may be more relevant with platelet-rich plasma (PRP). In this case, platelets are not stimulated by subendothelial molecules like collagen.
Mélusine Didelot +5 more
doaj +1 more source
Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head
Journal of International Medical Research, 2018 The two major theories of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) are apoptosis and ischaemia. The traditional theory implicates ischaemia as the main aetiological factor because the final common pathway of ONFH is ...
Qiankun Zhang, Jin L v, Lie Jin
doaj +1 more source
Survival analysis of coagulation disorders: A retrospective study with a 5-year follow-up
Heliyon, 2023 Objective: Rare bleeding disorders (RBDs) are the diseases in which patients experience a deficiency of coagulation factors. In the management of these disorders, surveillance is a significant challenge.
Arman Jahangiri +2 more
doaj +1 more source
Chinese Journal of Traumatology, 2017 Uncontrolled hemorrhage and subsequent trauma-induced coagulopathy (TIC) are still the principle causes for preventable death after trauma and early detection and aggressive management have been associated with reduced mortality.
Marc Maegele +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Influence of high-dose aprotinin treatment on blood loss and coagulation patterns in open-heart surgery [PDF]
, 1990 Intraoperative administration of the proteinase Inhibitor aprotinin causes reduction in blood loss and homologous blood requirement in patients undergoing cardiac surgery.
Dietrich, W. +6 more
core +1 more source
It Is Written in the Clot: Coagulation Assessment in Severe Burn Injury
European Burn JournalBackground: Coagulopathy in severe burn injury is associated with complications and mortality. Methods: We compared 3 tests (EXTEM, INTEM, FIBTEM) of rotational thromboelastometry (ROTEM), a viscoelastic coagulation assay (VCA), with conventional ...
Eirini Nikolaidou +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Research and Practice in Thrombosis and HaemostasisBackground: Factor XIII (FXIII) deficiency is a challenge in the diagnosis of rare bleeding disorders with inherited and acquired causes. Objectives: We evaluated consecutive cases tested for FXIII deficiency for insights on diagnosis.
Mohammed Abdullah Al Sharif +6 more
doaj +1 more source