Results 11 to 20 of about 123,153 (305)

The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]

open access: yes, 2002
In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Dolmans, Wil M.V.   +31 more
core   +1 more source

Modeling Disorders of Blood Coagulation in the Zebrafish [PDF]

open access: yesCurrent Pathobiology Reports, 2015
Hemostasis, the process of blood clot formation and resolution in response to vascular injury, and thrombosis, the dysregulation of hemostasis leading to pathological clot formation, are widely studied. However, the genetic variability in hemostatic and thrombotic disorders is incompletely understood, suggesting that novel mediators have yet to be ...
Colin A, Kretz   +2 more
openaire   +2 more sources

The International Prospective Glanzmann Thrombasthenia Registry: Pediatric Treatment and Outcomes

open access: yesTH Open, 2019
Background Standard treatment for Glanzmann thrombasthenia (GT), a severe inherited bleeding disorder, is platelet transfusion. Recombinant activated factor VII (rFVIIa) is reported to be effective in GT with platelet antibodies and/or refractoriness to ...
Rainer B. Zotz   +3 more
doaj   +1 more source

Peculiarities of blood coagulation disorders in patients with COVID-19

open access: yesТерапевтический архив, 2021
Aim. To study the relationship of hemostatic disorders with inflammation and estimate their role in the course and outcomes of COVID-19. Materials and methods. We examined 215 consecutive patients with moderate and severe forms of acute COVID-19.
Natalia G. Evtugina   +9 more
doaj   +1 more source

MODERN ASPECTS OF COAGULOPATHY DEVELOPMENT IN PATIENTS WITH COVID-19 INFECTION: LITERATURE REVIEW

open access: yesПроблеми екології та медицини, 2021
This review summarizes current knowledge about coagulation disorders associated with COVID-19 infection. Despite a significant amount of research, it is currently unclear whether COVID-19 is the direct cause of coagulopathic disorders or they occur as ...
M.O. Dudchenko   +2 more
doaj   +1 more source

Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2022
Introduction Contraceptives containing ethinylestradiol (EE) induce changes in the coagulation system and are associated with a risk of venous thromboembolism.
Annina H. Haverinen   +9 more
doaj   +1 more source

Validation of anaemia, haemorrhage and blood disorder reporting in hospital data in New South Wales, Australia

open access: yesBMC Research Notes, 2021
Objective Hospital data are a useful resource for studying pregnancy complications, including bleeding-related conditions, however, the reliability of these data is unclear.
Heather J. Baldwin   +5 more
doaj   +1 more source

Duplication of the prothrombin gene is associated with a significant increase in thrombin generation

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Prothrombin gene mutations can be associated with either a thrombotic or a bleeding risk. Genomic studies and coagulation workup can provide valuable information to better understand their clinical importance.
Annelie Siegemund   +6 more
doaj   +1 more source

Platelet aggregation impacts thrombin generation assessed by calibrated automated thrombography

open access: yesPlatelets, 2018
A calibrated automated thrombogram (CAT) is performed usually with human platelet-free plasma (PFP) but may be more relevant with platelet-rich plasma (PRP). In this case, platelets are not stimulated by subendothelial molecules like collagen.
Mélusine Didelot   +5 more
doaj   +1 more source

Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head

open access: yesJournal of International Medical Research, 2018
The two major theories of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) are apoptosis and ischaemia. The traditional theory implicates ischaemia as the main aetiological factor because the final common pathway of ONFH is ...
Qiankun Zhang, Jin L v, Lie Jin
doaj   +1 more source

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