Results 21 to 30 of about 50 (50)

CONGENITAL DISORDERS OF THE MECHANISM FOR COAGULATION OF BLOOD

Pediatrics, 1958
Ninety-two new cases of hemophilia A and 16 of hemophilia B are reported. The data, together with those from other reported series, suggest that hemophilia A and B comprise over 90% of all congenital hemorrhagic diseases due to defective formation of a fibrin clot. Of those with deficiencies of AHF or PTC, the incidence of PTC deficiency
P, DIDISHEIM, J H, LEWIS
openaire   +2 more sources

Activation of blood coagulation in autoimmune skin disorders

Expert Review of Clinical Immunology, 2009
The immune system and blood coagulation are simultaneously activated in several inflammatory systemic disorders, such as lupus erythematosus, rheumatoid arthritis and inflammatory bowel diseases. Proinflammatory cytokines, such as IL-6 and TNF-alpha, induce the expression of tissue factor, the main initiator of blood coagulation. Activated proteases of
M. Cugno, A. Tedeschi, C. Crosti, A.V. Marzano   +3 more
openaire   +4 more sources

[Acquired blood coagulation disorders].

Hamostaseologie, 2004
Acquired coagulopathies regularly result from underlying diseases such as liver failure or sepsis. Optimal treatment of these underlying diseases defines longterm prognosis. In a few coagulopathies, such as immunocoagulopathies, in a relevant portion of patients an underlying disease cannot be identified. Therapeutic modulation of haemostasis aiming at
openaire   +2 more sources

Molecular biology of blood coagulation disorders [PDF]

BioEssays, 1985
AbstractCurrent research into the molecular biology of blood‐clotting factors suggests that the basis of inherited bleeding disorders may soon be understood. In addition, the expression of cloned genes for the factors in mammalian cell lines provides the hope of pure factors being available for replacement therapy, uncontaminated with the causative ...
openaire   +1 more source

Blood Transfusion and Coagulation Disorders

2014
Resuscitation from hemorrhagic shock in trauma patients with active, ongoing bleeding is an area of active research and rapidly evolving best practice. Key elements discussed in this chapter include the damage control surgical model for rapid anatomic resolution, deliberate hypotensive resuscitation, early administration of red blood cells, plasma, and
Richard P. Dutton, L. Yvette Fouché-Weber   +1 more
openaire   +2 more sources

Cancer in persons with inherited blood coagulation disorders

Cancer, 1979
In order to assess the influence of an inherited blood coagulation disorder in individuals who developed cancer, a mail survey of physicians who care for individuals with a bleeding diathesis was evaluated. Sixty-one individuals in an estimated population of 10,500 with both disorders were identified.
Walter B. Forman, Walter B. Forman
openaire   +3 more sources

Blood coagulation disorders in septic patients

Wiener Medizinische Wochenschrift, 2010
Host defense and blood coagulation are tightly connected and interacting systems, necessary for the integrity of an organism. Complex mechanisms regulate the intensity of a host response to invading pathogens or other potentially dangerous situations.
openaire   +3 more sources

Hereditary Blood Coagulation Disorders: Management and Dental Treatment [PDF]

Journal of Dental Research, 2005
Patients with hereditary hemostatic disorders, characterized by a tendency to bleeding or thrombosis, constitute a serious challenge in the dental practice. Advances in the medical diagnosis of hemostatic disorders have exposed dental professionals to new patients not amenable to the application of the management protocols associated with other, more ...
Gerardo Gómez-Moreno, C. Arana, A. Cutando-Soriano, C. Scully   +3 more
openaire   +2 more sources

Surgery in children with congenital disorders of blood coagulation

Journal of Pediatric Surgery, 1971
Abstract Major surgery in patients with congenital disorders of blood coagulation such as hemophilia (factor VIII deficiency) and Christmas disease (factor IX deficiency) is becoming increasingly common. 1–3 This is true because of the more general availability of concentrated therapeutic materials and the development and standardization of tests ...
N.E. Dudley, M.H. Gough, P.B.A. Kernoff
openaire   +3 more sources

A User-Friendly App for Blood Coagulation Disorders

2018
There is a strong association between a suboptimal maternal environment and increased risk of developing age-associated diseases such as type 2 diabetes, obesity, and cardiovascular disease in the offspring. Blood clotting time may be altered in all of these conditions, and it is also an important factor that requires monitoring in postoperative and ...
Paul C. Guest, Johannes Vegt
openaire   +3 more sources