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Patient-Specific Modelling of Blood Coagulation
Blood coagulation represents one of the most studied processes in biomedical modelling. However, clinical applications of this modelling remain limited because of the complexity of this process and because of large inter-patient variation of the ...
N. Ratto +7 more
semanticscholar +1 more source
Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
core +2 more sources
Thrombosis and cardiovascular complications are common manifestations of a variety of pathological conditions, including infections and chronic inflammatory diseases.
Z. Łukasik, M. Makowski, J. Makowska
semanticscholar +1 more source
MODERN ASPECTS OF COAGULOPATHY DEVELOPMENT IN PATIENTS WITH COVID-19 INFECTION: LITERATURE REVIEW
This review summarizes current knowledge about coagulation disorders associated with COVID-19 infection. Despite a significant amount of research, it is currently unclear whether COVID-19 is the direct cause of coagulopathic disorders or they occur as ...
M.O. Dudchenko +2 more
doaj +1 more source
Coagulation disoders as a cause of juvenile uterine bleeding in 12–18 years adolescent girls
Obligatory detection of vWF blood levels, progesterone and testosterone levels in addition to routine tests are necessary to identify the causes of juvenile uterine bleeding.
V. V. Dmitriev +2 more
doaj +3 more sources
Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease. It is a group of chronic disorders characterized by inflammation of the gastrointestinal track with unknown etiology.
J. Matowicka-Karna
semanticscholar +1 more source
A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR +7 more
core +2 more sources
Platelet Biochemistry and Morphology after Cryopreservation [PDF]
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle +2 more
core +1 more source
Introduction Contraceptives containing ethinylestradiol (EE) induce changes in the coagulation system and are associated with a risk of venous thromboembolism.
Annina H. Haverinen +9 more
doaj +1 more source

