Results 121 to 130 of about 1,225,419 (385)

Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]

open access: yes, 1989
Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA   +5 more
core   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li   +9 more
wiley   +1 more source

Early dust evolution in protostellar accretion disks [PDF]

open access: yes, 2000
We investigate dust dynamics and evolution during the formation of a protostellar accretion disk around intermediate mass stars via 2D numerical simulations. Using three different detailed dust models, compact spherical particles, fractal BPCA grains, and BCCA grains, we find that even during the early collapse and the first 10,000 yr of dynamical disk
arxiv   +1 more source

Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting.

open access: yesBlood, 2016
Binding of coagulation factors to phosphatidylserine (PS)-exposing procoagulant-activated platelets followed by formation of the membrane-dependent enzyme complexes is critical for blood coagulation.
N. Podoplelova   +11 more
semanticscholar   +1 more source

Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation

open access: yesAdvanced Healthcare Materials, EarlyView.
TX hydrogel improves the delivery of different types of particulate bone grafts, maintaining them at the implantation sites, and resulting in favorable bone regenerative outcomes. Abstract Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor‐site bone harvesting can be associated with post‐surgical ...
Dax Calder   +9 more
wiley   +1 more source

Changes in Blood Viscosity With Synthetic Protease Inhibitors

open access: yesJournal of Pharmacological Sciences, 2003
We examined the effects on whole blood viscosity and coagulation time of various dosages of the synthetic low-molecular protease inhibitors gabexate mesilate and nafamostat mesilate with an oscillation-type viscometer.
Masahito Hitosugi   +6 more
doaj  

Portable Devices for In-Vitro Characterization Based on Ultrasound [PDF]

open access: yesarXiv, 2017
We propose a portable cartridge based lab-on-a-chip platform. The main sensing mechanism uses high frequency acoustic waves. Feasibility of two different transducers has been investigated for biological measurements. We used zincoxide (ZnO) based piezoelectric transducers for blood coagulation time measurements.
arxiv  

Coagulation Factors Level in Fresh Frozen Plasma in Rwanda [PDF]

open access: yes, 2014
Objectives: To determine the level of coagulation factors and inherited inhibitors in Fresh Frozen Plasma (FFP) and to evaluate Prothrombin Time and activated partial thrombin time in fresh frozen plasma.Design: Cross-sectional study.Setting: Jomo ...
Abdalah, F   +7 more
core   +2 more sources

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

open access: yesAdvanced Healthcare Materials, EarlyView.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez   +6 more
wiley   +1 more source

Blood coagulation factors and platelet response to drug-induced hepatitis and hepatosis in rats. [PDF]

open access: yesAnimal Model Exp Med, 2023
Korolova D   +8 more
europepmc   +1 more source

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