Results 161 to 170 of about 979,894 (292)

Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors [PDF]

, 2001
Herbert Nar, M. R. Bauer, Angela Schmid, Jean–Marie Stassen, Wolfgang Wienen, Henning Priepke, Iris K Kauffmann, Uwe J. Ries, Norbert Hauel   +8 more
openalex   +1 more source

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

Advanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao, Yi Wu, Haiyang Wang, Chenchun Zhang, Ying Zhu, Yan Jiang, Changyou Jiang, Qiumin Le, Xing Liu, Lan Ma, Feifei Wang   +10 more
wiley   +1 more source

Advances in the comprehensive mechanisms, diagnosis, and treatment of heatstroke-induced coagulopathy. [PDF]

Front Cell Dev Biol
Xiang C, Gao L, Liu X, Xiang J, Zhu B, Fu S, Zhao J, Song Q.   +7 more
europepmc   +1 more source

Five novel mutations in the gene for human blood coagulation factor V associated with type I factor V deficiency [PDF]

, 2001
Richard van Wijk, Karel Nieuwenhuis, Marijke van den Berg, Eric G. Huizinga, Brenda B. van der Meijden, Rob J. Kraaijenhagen, Wouter W. van Solinge   +6 more
openalex   +1 more source

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

Advanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu, Ting Liang, Hu Fang, Lu Fu, Dashi Deng, Xiyang Tan, Lisha Liu, Dongdong Tang, Haoxiang Zheng, Qiuxia Ding, Xiuqi Hou, Daquan Feng, Tao Tao, Song Wu   +13 more
wiley   +1 more source

Corticosterone Contributes to Context‐Triggered Retrieval of Morphine Withdrawal Memories by Acting on Basolateral Amygdala Neurons Projecting to Nucleus Accumbens Core

Advanced Science, EarlyView.
Context associated with morphine withdrawal elicits an increase in serum corticosterone levels. Corticosterone participates in CTR‐MWM by acting on MR, but not GR, in the BLA. MR in BLA→NAcC neurons mediates CTR‐MWM. MR increases presynaptic glutamate release and meanwhile participates in D1 receptor‐induced increases in presynaptic glutamate release ...
Zixuan Cao, Yaxian Wen, Yuanqi Chen, Yali Fu, Hao Yang, Chenshan Chu, Xinli Guo, Yu Yuan, Chao Lei, Huan Sheng, Da Shao, Li Yang, Dongyang Cui, Ming Chen, Bin Lai, Ping Zheng   +15 more
wiley   +1 more source

CKRT coagulation risk prediction and nursing feedback model based on intelligent algorithms. [PDF]

BMC Nephrol
Xu X, Chen M, Chen L, Huang K, Cao S, Gao W, Liu K, Wu B, Mao H.   +8 more
europepmc   +1 more source

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

, 1997
Karl‐Peter Hopfner, Hans Brandstetter, Annette Kärcher, Erhard Kopetzki, Robert Huber, Richard A. Engh, Wolfram Bode   +6 more
openalex   +2 more sources

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Coagulation profiles and platelet parameters among preeclampsia, eclampsia, and normotensive pregnant women attending Comprehensive Specialized Hospital maternity wards, Northwest Ethiopia. [PDF]

PLoS One
Alemu N, Teketelew BB, Admas S, Marelgn L, Eyayu Y, Woldu B.   +5 more
europepmc   +1 more source