Results 181 to 190 of about 1,225,419 (385)

The N-terminal sequences of blood coagulation factor X1 and X2 light chains. Mass-spectrometric identification of twelve residues of γ-carboxyglutamic acid in their vitamin K-dependent domains [PDF]

, 1978
Henning Thøgersen, Torben E. Petersen, Lars Sottrup‐Jensen, Staffan Magnusson, Howard R. Morris   +4 more
openalex   +1 more source

T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
This study describes the development of spike‐targeting T‐cell‐dependent bispecific full‐length human immunoglobulin Gs with enhanced efficacy in the treatment of COVID‐19. The significance of T‐cell‐based immunity during infection is highlighted. These results have significant implications for better clinical effectiveness of therapies for COVID‐19 ...
Wenyan Fu, Wei Zhang, Zhongshuai You, Guangyao Li, Chuqi Wang, Changhai Lei, Jian Zhao, Jin Hou, Shi Hu   +8 more
wiley   +1 more source

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng, Shiyuan Hua, Jiayu Zhou, Tangye Zeng, Jianke Chen, Lijian Su, Angfeng Jiang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

A rare homozygous missense GDF2 (BMP9) mutation causing PAH in siblings: Does BMP10 status contribute?

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 228-233, January 2023., 2023
Abstract Pulmonary arterial hypertension (PAH) is a disease characterized by pathological remodeling of the pulmonary vasculature causing elevated pulmonary artery pressures and ultimately, right ventricular failure from chronic pressure overload. Heterozygous pathogenic GDF2 (encoding bone morphogenetic protein 9 (BMP9)) variants account for some (>1%)
Paul Upton, Susan Richards, Angela Bates, Karen Y. Niederhoffer, Nicholas W. Morrell, Susan Christian   +5 more
wiley   +1 more source

Advances in Symbiotic Bioabsorbable Devices

Advanced Science, EarlyView.
This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu, Engui Wang, Zhou Li, Han Ouyang   +3 more
wiley   +1 more source

Copy number variants suggest different molecular pathways for the pathogenesis of bladder exstrophy

American Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 378-390, February 2023., 2023
Abstract Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11‐duplications detected in about 2%–3% of all patients.
Agneta Nordenskjöld, Samara Arkani, Maria Pettersson, Johanna Winberg, Jia Cao, Magdalena Fossum, Magnus Anderberg, Gillian Barker, Gundela Holmdahl, Johanna Lundin   +9 more
wiley   +1 more source

Comparative studies between humans and golden Syrian hamsters via thromboelastography

Animal Models and Experimental Medicine
Background Thromboelastography (TEG) is a widely utilized clinical testing method for real‐time monitoring of platelet function and the thrombosis process. Lipid metabolism disorders are crucial risk factors for thrombosis.
Ze Yang, Lili Xie, Jingjing Ba, Simin Zan, Letong Zhang, Xinyi Zhang, Yang Yu   +6 more
doaj   +1 more source

Kinetic determination of blood coagulation Factor XIII in plasma. [PDF]

, 1985
László Muszbek, János Polgár, László Fésüs   +2 more
openalex   +1 more source

ODSEI Chip: An Open 3D Microfluidic Platform for Studying Tumor Spheroid‐Endothelial Interactions

Advanced Science, EarlyView.
The ODSEI chip, a novel 3D‐microarray platform, co‐cultures tumor spheroids on the vasculature, enabling drug treatment and specific spheroid extraction. The ODSEI chip demonstrates reduced tamoxifen sensitivity within spheroids when interacting with endothelial cells.
Jooyoung Ro, Junyoung Kim, Juhee Park, Yongjun Choi, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Electret‐Inspired Charge‐Injected Hydrogel for Scar‐Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation

Advanced Science, EarlyView.
This study presents an electret‐inspired charge‐injected self‐powered hydrogel (QOSP) for the treatment of second‐degree burn wounds infected with Staphylococcus aureus and Pseudomonas aeruginosa. The hydrogel effectively eliminates bacteria and enhances cell proliferation through electrical stimulation, thereby accelerating wound healing. Additionally,
Mujie Liu, Yuheng Wang, Haodong Wang, Lihong Qi, Yuxuan Shang, Jiajie Song, Xiulong Feng, Yiwei Chen, Waqar Ali Memon, Yuping Shen, Xiaodong Wu, Jiangbei Cao, Yifan Zhao, Zhuangde Jiang, Dingxin Liu, Shareen Shafique, Shengtao Li, Guanghao Lu, Zhixiang Wei, Zhijie Liu, Kun Zhou, Yuping Quan, Xiaoyu Zhang, Xin Zou, Xuefeng Wang, Na Liu, Yaqing Zhang, Yiwei Hu, Chao Han, Wen Wang   +29 more
wiley   +1 more source