Results 1 to 10 of about 1,533,152 (153)

Local hemostasis disorders underlying endometric pathology

open access: yesАкушерство, гинекология и репродукция, 2021
Introduction. Hemostasis is an equilibrium system that performs 2 bidirectional tasks: on the one hand, it prevents bleeding development, whereas on the other hand, it counters thrombogenesis.
E. Iu. Iupatov   +6 more
doaj   +1 more source

Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells

open access: yesImmunity, Inflammation and Disease, 2023
Background Vascular diseases are highly associated with inflammation and thrombosis. Elucidating links between these two processes may provide a clearer understanding of these diseases, allowing for the design of more effective treatments. The activation
Christopher T. Freda   +3 more
doaj   +1 more source

Tissue factor and tissue factor pathway inhibitor [PDF]

open access: yesAnaesthesia, 2004
Summary The classical ‘cascade/waterfall’ hypothesis formulated to explain in vitro coagulation organised the amplification processes into the intrinsic and extrinsic pathways.
G C, Price, S A, Thompson, P C A, Kam
openaire   +2 more sources

Endothelial dysfunction and immunothrombosis in sepsis

open access: yesFrontiers in Immunology, 2023
Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection.
Eleni Maneta   +10 more
doaj   +1 more source

A First-In-Class, Humanized Antibody Targeting Alternatively Spliced Tissue Factor: Preclinical Evaluation in an Orthotopic Model of Pancreatic Ductal Adenocarcinoma

open access: yesFrontiers in Oncology, 2021
In 2021, pancreatic ductal adenocarcinoma (PDAC) is the 3rd leading cause of cancer deaths in the United States. This is largely due to a lack of symptoms and limited treatment options, which extend survival by only a few weeks.
Clayton S. Lewis   +10 more
doaj   +1 more source

Tissue Factor-Enriched Neutrophil Extracellular Traps Promote Immunothrombosis and Disease Progression in Sepsis-Induced Lung Injury

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
BackgroundPatients with sepsis may progress to acute respiratory distress syndrome (ARDS). Evidence of neutrophil extracellular traps (NETs) in sepsis-induced lung injury has been reported.
Hao Zhang   +16 more
doaj   +1 more source

Tissue factor controversies [PDF]

open access: yesThrombosis Research, 2012
Tissue factor plays a primary role in both hemorrhage control and thrombosis depending upon whether its presentation is extravascular or intravascular. The molecular architecture and function of the tissue factor molecule and its role in the activations of factor IX and factor X have been elegantly elucidated but controversies prevail with respect to ...
Kenneth G, Mann   +2 more
openaire   +2 more sources

Value of multimodal MRI in evaluation of tissue factor expression in glioblastoma

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the correlation between multimodal magnetic resonance imaging (MRI) and expression of tissue factor (TF) in glioblastoma (GBM), and investigate the values of MRI parameters as imaging markers for TF.
ZHOU Bo   +5 more
doaj   +1 more source

Potential biochemical markers of chronic bronchitis

open access: yesБюллетень сибирской медицины, 2021
The review systematizes modern data on the biochemical markers that can clarify the nature and the course of chronic bronchitis. The article describes markers associated with bronchopulmonary pathology, such as tumor necrosis factor alpha (TNFα ...
E. A. Kurtukov, Yu. I. Ragino
doaj   +1 more source

Tissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis

open access: yesFrontiers in Immunology, 2023
ObjectivesRecent studies supported coagulation involvement in multiple sclerosis, an inflammatory-demyelinating and degenerative disease of the central nervous system. The main objectives of this observational study were to identify the most specific pro-
Tatiana Koudriavtseva   +21 more
doaj   +1 more source

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