Results 41 to 50 of about 3,969,245 (300)
Tissue Factor–Factor VIIa Signaling [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 How does tissue factor (TF), whose principle role is to support clotting factor VIIa (FVIIa) in triggering the coagulation cascade, affect various pathophysiological processes? One of the answers is that TF interaction with FVIIa not only initiates clotting but also induces cell signaling via activation of G-protein–coupled protease activated receptors
L Vijaya Mohan, Rao, Usha R, Pendurthi
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The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]
, 1993 The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
BUCHETON, A +3 more
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Inhibitors of Factor VIIa/Tissue Factor [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 The formation of the proteolytic complex composed of the serine protease Factor VIIa and the cell-associated glycoprotein tissue factor (FVIIa/TF) initiates a cascade of amplified zymogen activation reactions leading to thrombus formation. The critical role of the coagulation cascade in pathological thrombosis has been the basis for significant efforts
Rebecca A, Shirk, George P, Vlasuk
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The role of coagulation hemostasis for development of early-onset preeclampsia in low-risk patients
Акушерство, гинекология и репродукция, 2022 Aim: to determine a role of specific parameters of coagulation hemostasis for development of severe early-onset preeclampsia (еPE) in low-risk patients.Materials and Methods.
M. G. Nikolaeva +4 more
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miR-34a-/- mice are susceptible to diet-induced obesity [PDF]
, 2016 Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H. +7 more
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Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 Series Editor: Nigel Mackman Mark B. Taubman ATVB In Focus Tissue Factor: Past, Present, and Future Articles in this series: •Mackman N. Tissue factor: past, present, and future. Arterioscler Thromb Vasc Biol 2009;29:1986–1988. •Butenas S, Orfeo T, Mann KG. Tissue factor in coagulation: which? where? when?
Nigel, Mackman, Mark, Taubman
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Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study [PDF]
, 2019 BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers.
Brenner, H. +17 more
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Role of pyroptosis in hemostasis activation in sepsis
Frontiers in Immunology, 2023 Sepsis is frequently associated with hemostasis activation and thrombus formation, and systematic hemostatic changes are associated with a higher risk of mortality.
Chengrui Zhu +3 more
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Vascular miR‐181b controls tissue factor‐dependent thrombogenicity and inflammation in type 2 diabetes [PDF]
, 2020 BACKGROUND: Diabetes mellitus is characterized by chronic vascular inflammation leading to pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform alternatively-spliced (as) TF. Blood-borne TF promotes factor (
Chakraborty, Aritra +14 more
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Emerging Microbes and Infections, 2020 We previously made the hypothesis that STING contributes to COVID-19. The present review detail new arguments for over-activation of STING pathways in COVID-19, following the description of hyper-coagulability and Kawasaki-like diseases in children ...
Jean-Marie Berthelot +2 more
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