Results 41 to 50 of about 8,614,068 (306)
Cell Adhesion & Migration, 2021 Tissue factor (TF) has been extensively studied for tumor metastasis, but its role in mediating cancer cell adhesion to vasculature remains unknown. This study aimed to measure the ability of TF to mediate the adhesion of breast cancer cells to human ...
Yanling Jin +9 more
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Molecules, 2023 Chuanxiong rhizoma (CX) has been utilized for centuries as a traditional herb to treat blood stasis syndromes. However, the pharmacological mechanisms are still not completely revealed.
Shasha He +3 more
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COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +10 more
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Inhibitors of Factor VIIa/Tissue Factor [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 The formation of the proteolytic complex composed of the serine protease Factor VIIa and the cell-associated glycoprotein tissue factor (FVIIa/TF) initiates a cascade of amplified zymogen activation reactions leading to thrombus formation. The critical role of the coagulation cascade in pathological thrombosis has been the basis for significant efforts
Rebecca A, Shirk, George P, Vlasuk
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Artificial neural networks in hard tissue engineering : another look at age-dependence of trabecular bone properties in osteoarthritis [PDF]
, 2014 Artificial Neural Network (ANN) model has been developed to correlate age of severely osteoarthritic male and female specimens with key mechanical and structural characteristics of their trabecular bone.
Natasha A Khovanova +5 more
core +1 more source
Tissue Factor and Atherothrombosis
Current Pharmaceutical Design, 2015 Tissue factor (TF) is known to be the key element in the initiation of the extrinsic pathway of the coagulation cascade and appears to be a critical determinant of atherosclerotic plaque thrombogenicity. TF is needed to produce thrombin from prothrombin. In the extrinsic pathway, TF activates factor Vll. TF is expressed mainly on subendothelial tissues,
D, Saha +4 more
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Tissue Factor–Factor VIIa Signaling [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 How does tissue factor (TF), whose principle role is to support clotting factor VIIa (FVIIa) in triggering the coagulation cascade, affect various pathophysiological processes? One of the answers is that TF interaction with FVIIa not only initiates clotting but also induces cell signaling via activation of G-protein–coupled protease activated receptors
L Vijaya Mohan, Rao, Usha R, Pendurthi
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The role of coagulation hemostasis for development of early-onset preeclampsia in low-risk patients
Акушерство, гинекология и репродукция, 2022 Aim: to determine a role of specific parameters of coagulation hemostasis for development of severe early-onset preeclampsia (еPE) in low-risk patients.Materials and Methods.
M. G. Nikolaeva +4 more
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Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]
, 2013 This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Kouser, L +23 more
core +1 more source
Research and Practice in Thrombosis and HaemostasisBackground: Mim8 is a next-generation activated factor (F)VIII–mimetic, bispecific antibody, currently in clinical development for the prophylactic treatment of hemophilia A.
Wan Hui Ong Clausen +4 more
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