Results 51 to 60 of about 2,653,429 (308)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

The role of tissue factor in normal pregnancy and in the development of preeclampsia: A review

Biomedical Papers, 2015
Background: Tissue factor (TF) is a key element for normal gestation, especially in the first trimester. TF levels are hence raised in pregnancy, producing an adaptive hypercoagulable state.
Jana Prochazkova, Ludek Slavik, Jana Ulehlova, Martin Prochazka   +3 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Activation of TF-Dependent Blood Coagulation Pathway and VEGF-A in Patients with Essential Thrombocythemia

Medicina, 2019
Background and objectives: Recent studies suggest that a vascular endothelial growth factor (VEGF-A) may be involved in the thrombotic process by stimulating the expression of tissue factor in vascular endothelial cells.
Grażyna Gadomska, Katarzyna Ziołkowska, Joanna Boinska, Jan Filipiak, Danuta Rość   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion [PDF]

, 2010
Background: Human tissue kallikrein (hK1) generates vasodilator kinins from kininogen and promotes angiogenesis by kinin-dependent and kinin-independent mechanisms.
Sharman, JA, Mangialardi, GMVU, Sharman, J.A., J A Sharman, Pignatelli, M., Campagnolo, P., H. Zadeh M, P Dominek, Spinetti G, Kränkel, N, Madeddu, P, Kränkel N, H-Zadeh, M., Emanueli, C., M Pignatelli, Spinetti, G., M Chilosi, H-Zadeh, M, A Caporali, Campagnolo P, Dominek, P., Pignatelli M, P Madeddu, Mangialardi G, M H-Zadeh, Emanueli C, N Kränkel, Caporali, A, Pignatelli, M, Spinetti, G, Madeddu, P., Chilosi, M., Mangialardi, G, Emanueli, C, Dominek, PK, Kraenkel, N, Sharman, J A, G Mangialardi, Caporali A, Dominek P, Sharman JA, Madeddu, PR, Mangialardi, G., CHILOSI, Marco, P Campagnolo, Chilosi, M, G Spinetti, Campagnolo, P, Madeddu P., Kränkel, N., C Emanueli, Caporali, A., Caporali, A; id_orcid, Dominek, P   +53 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

VEGF-expressing mesenchymal stem cells for improved angiogenesis in regenerative medicine : a bone tissue engineering approach [PDF]

, 2011
Rapid vascularization of tissue-engineered grafts is a major bottleneck in the development of regenerative medicine approaches. In order to overcome this limitation, we aimed to develop a bone tissue engineering strategy combining cell therapy with pro ...
Helmrich, Uta
core   +1 more source

PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting

Frontiers in Physiology, 2021
Coagulation abnormalities and increased risk of atherothrombosis are common in patients with chronic kidney diseases (CKD). Mechanisms that alter renal hemostasis and lead to thrombotic events are not fully understood.
Abishek Iyer, Abishek Iyer, Tyrone L. R. Humphries, Evan P. Owens, Kong-Nan Zhao, Paul P. Masci, David W. Johnson, David W. Johnson, David Nikolic-Paterson, Glenda C. Gobe, Glenda C. Gobe, David P. Fairlie, David P. Fairlie, David A. Vesey, David A. Vesey   +14 more
doaj   +1 more source