Results 71 to 80 of about 8,614,068 (306)

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Coagulation markers and functional outcome in acute ischemic stroke: Impact of intensive versus standard hyperglycemia control

Research and Practice in Thrombosis and Haemostasis, 2021
Objective Alterations in coagulation could mediate functional outcome in patients with hyperglycemia after acute ischemic stroke (AIS). We prospectively studied the effects of intensive versus standard glucose control on coagulation markers and their ...
Nina T. Gentile, A. Koneti Rao, Hannah Reimer, Fabiola Del Carpio‐Cano, Viswanathan Ramakrishnan, Qi Pauls, William G. Barsan, Askiel Bruno, for the iSPOT, Neurological Emergencies Treatment Trials Network (NETT) Investigators   +8 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner

Upsala Journal of Medical Sciences, 2019
Background: Tissue factor (TF) combined with its ligand FVII initiates blood coagulation and intracellular signaling. Obese and type 2 diabetic subjects have increased TF expression in their adipose tissue and an increased risk for thrombotic ...
Desirée Edén, Grigorios Panagiotou, Dariush Mokhtari, Jan W. Eriksson, Mikael Åberg, Agneta Siegbahn   +5 more
doaj   +1 more source

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype

Frontiers in Cell and Developmental Biology, 2022
Tissue factor (TF) is crucial for embryogenesis, as mice lacking TF are embryonically lethal (E10.5). This lethality may be attributed to defects in vascular development and circulatory failure, suggesting additional roles for TF in embryonic development
Saravanan Subramaniam, Saravanan Subramaniam, Jiandong Liu, Jiandong Liu, Craig Fletcher, Ramani Ramchandran, Hartmut Weiler   +6 more
doaj   +1 more source

Spiral Tissue Microarrays as Next Evolutionary Step in the High-density Tissue Microarray Technology [PDF]

, 2010
Tissue microarray (TMA) is a well-established technique that connects basic research with clinical applications that allow the validation of many pathobiologic events from gene expression dysregulation to genomic aberrations.
Junya Fukuoka, Matthias Hofer, Tomonori Tanaka, Takeshi Uemura, Lucian Chirieac, Sayaka Tominaga, Takashi Hori, Ryo Ohsawa   +7 more
core  

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins [PDF]

, 2006
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins
Scorilas, Andreas, Malm, Johan,, Courty, Yves, Ulf-Håkan Stenman, Lundwall, Åke,, Yousef, George M, Georgia Sotiropoulou, Lois J. Maltais, Talieri, Maroulio, Olsson, A Yvonne, Yousef, George, Talieri, M., Malm, Johan, Carsten Stephan, Stephan, Carsten, Blaber, M., Liija, H., Malm, J., Fritz, Hans, Blaber, Michael, Clements, Judith A, Lundwall, A., Lilja, Hans, Andreas Scorilas, Scorilas, A., Olsson, A. Yvonne, Hans Fritz, Judith A. Clements, Fritz, H., Lundwall, Åke, Constantina Petraki, Maltais, Lois J, Sotiropoulou, Georgia, Clements, J A, Clements, Judith, Lund University., Vimla Band, A. Yvonne Olsson, Band, Vimla, Maroulio Talieri, Stephan, C., Lilja, Hans,, Yousef, G M, Petraki, Constantina, Sotiropoulou, G., Courty, Y., Eleftherios P. Diamandis, Åke Lundwall, Michael Blaber, Diamandis, Eleftherios P, Hans Lilja, Stenman, Ulf-Hakan, Diamandis, E P, Maltais, L J, Petraki, C., George M. Yousef, Yves Courty, Olsson, A Y, Band, V., Maltais, Lois, Diamandis, Eleftherios, Johan Malm   +61 more
core   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source