Results 81 to 90 of about 2,653,429 (308)

Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes [PDF]

, 2007
Objective: To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints.
A. Marsano, Jakob, M., I. Martin, E. Kon, Tognana, E., Nehrer, S., D.M. Salter, E. Tognana, Marsano, A., Adesida, A., Hardingham, T., Salter, D.M., S.J. Millward-Sadler, Salter, D. M., A. Adesida, S. Nehrer, T. Hardingham, Chiari-Grisar, C., Kon, E., Martin, I., Millward-Sadler, S. J., M. Jakob, C. Chiari-Grisar, Millward-Sadler, S.J.   +23 more
core   +1 more source

Platelets and tissue factor

Platelets, 2005
Tissue factor (TF) is the most important initiator of intravascular coagulation. This article will review published evidence on the contribution of platelets to TF exposure to the circulating blood. The following mechanisms will be discussed: decryption of monocyte TF by platelets, contribution of platelets to TF expression in leukocytes, platelet ...
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A tissue kallikrein in the synovial fluid of patients with rheumatoid arthritis [PDF]

, 1989
Tissue kallikrein is an enzyme that forms the vasoactive peptide kallidin from an endogenous substrate L-kininogen. Tissue kallikrein has been identified in joint fluids and in inflammatory infiltrates within synovial membranes.
Bhoola, K. D., Selwyn, B. M., Dieppe, P. A., Figueroa, C. D., Swan, A., Fink, Edwin   +5 more
core   +1 more source

Dependence of clot structure and fibrinolysis on apixaban and clotting activator

Research and Practice in Thrombosis and Haemostasis
Background: Anticoagulants prevent the formation of potentially fatal blood clots. Apixaban is a direct oral anticoagulant that inhibits factor (F)Xa, thereby impeding the conversion of prothrombin into thrombin and the formation of blood clots.
Rebecca A. Risman, Mitali Shroff, Julie Goswami, Valerie Tutwiler   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

A coacervate-based platform for growth factor delivery [PDF]

, 2013
Growth factors participating in a variety of biological processes have great potential in regenerative medicine. However, unprotected growth factors degrade quickly and have little efficacy at tissue repair.
Chu, Hunghao
core  

PREDICTORS OF ADVERSE CLINICAL COURSE OF CORONARY HEART DISEASE: THE RESULTS FROM DYNAMICAL OBSERVATION

Российский кардиологический журнал, 2018
Aim. To reveal the molecular genetic predictors of adverse clinical course of coronary heart disease (CHD).Material and methods. A clinical genetic investigation performed, of 567 CHD patients, of those 199 underwent dynamic follow-up. Genotypes Pro12Pro,
E. V. Shlyakhto, Е. G. Sergeeva, О. А. Berkovich, S. N. Pchelina, М. I. Zarayskiy, Zh. I. Ionova, E. A. Polyakova, E. I. Baranova   +7 more
doaj   +1 more source

Antiviral anticoagulation

Research and Practice in Thrombosis and Haemostasis, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a novel envelope virus that causes coronavirus disease 2019 (COVID‐19). Hallmarks of COVID‐19 are a puzzling form of thrombophilia that has elevated D‐dimer but only modest effects on other ...
Edward L. G. Pryzdial, Michael R. Sutherland, Bryan H. Lin, Marc Horwitz   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source