Results 191 to 200 of about 979,894 (292)

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

Promucetin, a new C-type lectin-like protein modulates coagulation by activating platelets via GPIb. [PDF]

open access: yesJ Venom Anim Toxins Incl Trop Dis
Yu XQ, Zhang QY, Zhou ST, Lu QY, Sun QY.
europepmc   +1 more source

Lenvatinib Plus Paclitaxel as Second‐Line Therapy for Advanced Gastric Cancer Patients: A Dose Escalation Exploratory Study

open access: yesAdvanced Science, EarlyView.
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou   +8 more
wiley   +1 more source

An Osteoconductive Janus Hydrogel with Full Barrier Protection and Adaptable Degradation Properties for Superior Bone Regeneration

open access: yesAdvanced Science, EarlyView.
The filler‐barrier hydrogel system developed by dual‐network Janus structural strategy breaks through the difficulty of a single hydrogel to combine barrier protection with bone regeneration, and realizes the regeneration‐material degradation adaptation for the field of mandibular regeneration.
Yanhui Lu   +14 more
wiley   +1 more source

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

open access: yesAdvanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen   +7 more
wiley   +1 more source

Preventive correction of fibrinolysis with epsilon aminocaproic acid detected by thromboelastometry during liver transplantation. [PDF]

open access: yesArq Bras Cir Dig
Nascimento JCR   +6 more
europepmc   +1 more source

Interfacial Roughness‐Reinforced Magnetic Nanosheet Colloidal Gels for Stable Embolization and Magnetothermal Therapy of Hepatic Tumor

open access: yesAdvanced Science, EarlyView.
A rough‐interface reinforcement strategy is implemented to construct nanosheet‐mica‐based magnetic colloidal hydrogels with enhanced mechanical robustness and injectability. These hydrogels achieve stable vascular embolization and effective magnetothermal performance, offering synergistic therapeutic benefits in hepatic tumor treatment.
Xingyu Liu   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy