Results 231 to 240 of about 979,894 (292)

Tissue Factor Initiated Blood Coagulation

Frontiers in Bioscience, 2006
Tissue factor (TF) is the cellular receptor and cofactor for blood coagulation factor (F) VII. Exposure of flowing blood to cells that express TF leads to the initiation of blood coagulation. Blood coagulation is tightly regulated to generate a local fibrin clot at the site of vascular injury without compromising blood flow in the vasculature.
Gomez, K, McVey, JH
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Inhibitors of blood coagulation factor XIII

Analytical Biochemistry, 2020
The blood coagulation factor XIII (FXIII) plays an essential role in the stabilization of fibrin clots. This factor, belonging to the class of transglutaminases, catalyzes the final step of secondary hemostasis, i.e. the crosslinking of fibrin polymers. These crosslinks protect the clots against premature fibrinolysis.
Thomas Schmitz, Charlotte A. Bäuml, Diana Imhof   +2 more
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THE STABILITY OF COAGULATION FACTORS IN STORED BLOOD

Australian and New Zealand Journal of Surgery, 1982
The complete coagulation profile of citrate phosphate dextrose (CPD) stored blood has been studied during 21 days storage at 4°C. Ten donations were studied at zero, one, seven, 14 and 21 days. One donation contained small clots and was studied separately. Activities of factors I, II, IX, XII or XIII did not deteriorate significantly.
J.V. Lloyd, J.A. Hondow, W. J. Russell, B. M. Duncan   +3 more
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A Photometric Assay for Blood Coagulation Factor XIII [PDF]

Thrombosis and Haemostasis, 1991
SummaryAn assay for a direct photometric determination of F XIII in untreated and undiluted plasma was developed. In a one-step procedure F XIII is activated by thrombin and Ca2+ and crosslinks glycine-ethylester to a specific glutamine containing peptide substrate.
Angela Aab, Werner Stüber, Karl Dr Fickenscher   +2 more
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Characterisation of blood coagulation factor XIT475I

Thrombosis and Haemostasis, 2005
SummaryPCR-SSCP and DNA sequence analysis of a factor XI (FXI) deficient patient (FXI:C 39 U/dL; FXI:Ag 27 U/dL) identified a C to T transition in exon 12 of the FXI gene (F11 c.1521C>T) that predicts the substitution of Thr475 by Ile (FXIT475I) within the serine protease domain of FXI.
McVey, JH, Lal, K, Imanaka, Y, Kemball-Cook, G, Bolton-Maggs, PH, Tuddenham, EG   +5 more
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Factor XIII of blood coagulation in human monocytes

Thrombosis Research, 1985
The presence of Factor XIII subunit a was demonstrated in human monocytes by immunoperoxidase staining using specific antisera against Factor XIII and its subunits. This finding was verified by immunobiochemical techniques, as well. In an immunoblotting system after SDS polyacrylamide gel electrophoresis of denatured monocyte homogenate a protein band ...
Muszbek, László, Szegedi, Gyula, Polgár, János, Kávai, Mária, Ádány, Róza   +4 more
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Transient blood thinning during extracorporeal blood purification via the inactivation of coagulation factors by hydrogel microspheres

Nature Biomedical Engineering, 2021
Xin Song, Haifeng Ji, Yupei Li, Yuqin Xiong, Li Qiu, Rui Zhong, Meng Tian, J. Kizhakkedathu, Baihai Su, Q. Wei, Weifeng Zhao, Changsheng Zhao   +11 more
semanticscholar   +1 more source

Blood coagulation factor XIII and factor XIII deficiency

Blood Reviews, 2016
Factor XIII (FXIII) is a multifunctional pro-γ-transglutaminase that, in addition to its well-known role in hemostasis, has a crucial role in angiogenesis, maintenance of pregnancy, wound healing, bone metabolism, and even cardio protection. FXIII deficiency (FXIIID) is a rare bleeding disorder (RBD) with an estimated incidence of one per two million ...
Jamal Rashidpanah, Akbar Dorgalaleh
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Tissue Factor and the Initiation of Blood Coagulation

1987
In the two decades since the introduction of the cascade and waterfall models of blood coagulation 1,2, the investigative emphasis has been on the “intrinsic” system of coagulation. In this system, coagulation is initiated by Hageman factor, which is presumably activated by virtue of an interaction with a “surface”, and proceeds by way of several ...
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Disorders of Blood Coagulation Factors

1985
Any patient suspected of having a disorder of blood coagulation, either from family history or repeated bleeding episodes occurring spontaneously or secondary to trauma, should undergo appropriate diagnostic testing prior to the onset of pregnancy. The levels of the majority of coagulation factors increase during pregnancy, making accurate diagnosis of
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