Results 111 to 120 of about 5,195,311 (386)

Seroprevalence of infectious markers & their trends in blood donors in a hospital based blood bank in north india

open access: yesThe Indian journal of medical research, 2015
Background & objectives: Hepatitis B virus (HBV), human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis infections pose a great threat to blood safety.
R. Makroo   +4 more
semanticscholar   +1 more source

Will There Be Blood? Incentives and Substitution Effects in Pro-social Behavior [PDF]

open access: yes
We examine how economic incentives affect pro-social behavior through the analysis of a unique dataset with information on more than 14,000 American Red Cross blood drives.
Lacetera, Nicola   +2 more
core   +3 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

A Survey of Motivations for 9/11, Hurricane Katrina and General Lapsed Donors in Northern Vermont [PDF]

open access: yes, 2008
Introduction: Despite rising demand, blood donation has remained stagnant in recent years, except for donation spikes that occurred in periods after major national crises such as the September 11th attacks in 2001 and Hurricane Katrina in August 2005 ...
Balderama, G   +10 more
core   +1 more source

Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin α\(_4\)β\(_7\) [PDF]

open access: yes, 2009
Background: The Step Study was a randomized trial to reduce HIV infection through vaccination with an adenovirus type 5-based gag/pol/nef construct; analysis following early cessation of the trial revealed an excess of HIV seroconversion in Ad5 ...
Chakupurakal, Geothy   +4 more
core   +1 more source

FREQUENCY OF KELL ANTIGENS (K & K) AMONG BLOOD DONORS OF NORTHERN PAKISTAN

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To determine the frequency of Kell blood group antigens (K and k) in blood donors from northernPakistan. Study Design: Cross sectional study. Place and Duration of Study: The study was carried out at immunohaematology department of Armed
Asad Mehmood   +3 more
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Impact of Deferral for Low Hemoglobin on Donor Return [PDF]

open access: yes, 2018
Introduction. A consistent blood supply to support life-saving transfusions relies on regular and repeat volunteer blood donations. In this study, we focused on donors previously deferred for low-hemoglobin (Hb) levels to better understand the value of ...
Aiken, Ashley   +7 more
core   +1 more source

Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]

open access: yes, 2018
The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky   +3 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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