Results 91 to 100 of about 6,494,932 (399)

A 21-day Daniel fast with or without krill oil supplementation improves anthropometric parameters and the cardiometabolic profile in men and women

open access: yesNutrition & Metabolism, 2012
Background The Daniel Fast is a vegan diet that prohibits the consumption of animal products, refined foods, white flour, preservatives, additives, sweeteners, flavorings, caffeine, and alcohol.
Trepanowski John F   +3 more
doaj   +1 more source

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

open access: yes, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V   +12 more
core   +4 more sources

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

open access: yesFEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui   +3 more
wiley   +1 more source

Insufficient control of blood pressure and incident diabetes [PDF]

open access: yes, 2009
OBJECTIVE: Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control.
CHINALI, MARCELLO   +8 more
core   +1 more source

The relationships between blood pressure, blood glucose, and bone mineral density in postmenopausal Turkish women

open access: yesTherapeutics and Clinical Risk Management, 2015
Huseyin Altug Cakmak,1 Burcu Dincgez Cakmak,2 Ayse Ender Yumru,3 Serkan Aslan,4 Asim Enhos,1 Ali Kemal Kalkan,4 Ebru Inci Coskun,5 Abdullah Serdar Acikgoz,6 Suat Karatas3 1Department of Cardiology, Mustafakemalpasa Government Hospital, Bursa ...
Cakmak HA   +8 more
doaj  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats [PDF]

open access: yes, 2018
Aim: Diabetes in pregnancy is a major burden with acute and long-term consequences. Its treatment requires adequate diagnosis and monitoring of therapy. Many experimental research on diabetes during pregnancy has been performed in rats.
Alenina, Natalia   +11 more
core   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Social representations of feeding people with type-2 diabetes mellitus [PDF]

open access: yes, 2016
The aim of this study was to analyze the social representations of the diets 34 patients of the Brazilian public primary care service diagnosed with type- 2 diabetes mellitus, according to how they represent their identity.
Amorim, Maria Marta Amancio   +2 more
core   +1 more source

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