Results 241 to 250 of about 420,739 (331)

Blood Coagulation in Uremic Patients Before and After Hemodialysis and Transplantation of the Kidney [PDF]

open access: yes, 1966
Marchioro, TL   +4 more
core   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

open access: yesAdvanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen   +18 more
wiley   +1 more source

An Injectable BMP‐2‐Releasing Porous Hydrogel Regulating the Paracrine Effects of ADSCs Promotes Tendon‐to‐Bone Healing in Rotator Cuff Repair

open access: yesAdvanced Science, EarlyView.
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan   +11 more
wiley   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

open access: yesAdvanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao   +17 more
wiley   +1 more source

THE EFFECT OF IPRONIAZID AND IMIPRAMINE ON THE BLOOD PLATELET 5‐HYDROXYTRYPTAMINE LEVEL IN MAN [PDF]

open access: bronze, 1960
Elizabeth F. Marshall   +3 more
openalex   +1 more source

Scaffolding Protein ENH Promotes Tumor Angiogenesis and Growth Through Macrophage Recruitment and Polarization

open access: yesAdvanced Science, EarlyView.
In tumor cells, ENH prompts the interaction between YAP and KPNA2. This interaction enables YAP to translocate into the nucleus, where it enhances the transcription of CCL5. Consequently, this up‐regulation of CCL5 drives the infiltration of tumor‐associated macrophages (TAMs) and their polarization toward the M2 phenotype, ultimately facilitating ...
Yueli Shi   +14 more
wiley   +1 more source

Effects of functionalized silver nanoparticles on aggregation of human blood platelets. [PDF]

open access: yesInt J Nanomedicine, 2019
Hajtuch J   +6 more
europepmc   +1 more source

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