Results 301 to 310 of about 410,702 (329)

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Versatile Standing Wave Generation Between Arbitrarily Oriented Surfaces Using Acoustic Metasurface Deflectors and Retroreflectors

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A novel method for generating versatile standing wave fields using an acoustic metasurface deflector and retroreflector is introduced. By overcoming traditional constraints of parallel surfaces, the approach enables customizable wave patterns and enhances applications in particle manipulation.
Chadi Ellouzi, Farhood Aghdasi, Ali Zabihi, Amir K. Miri, Chen Shen   +4 more
wiley   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

Regulating billions of blood platelets: glycans and beyond.

Blood, 2015
Grozovsky R, Giannini S, Falet H, Hoffmeister KM.   +3 more
europepmc   +1 more source

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Blood platelet biochemistry

Thrombosis Research, 2012
Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug ...
Hendrik B. Feys, Katleen Broos, Simon F. De Meyer, Hans Deckmyn, Karen Vanhoorelbeke   +4 more
openaire   +3 more sources

Blood Platelets and Platelet Transfusions

Archives of Internal Medicine, 1961
The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
openaire   +3 more sources

Blood platelet production and morphology

Thrombosis Research, 2012
Circulating platelets are highly specialized cells produced by megakaryocytes (Mks) that participate in hemostatic and inflammatory functions. Despite their critical role little is known about the molecular mechanisms involved in their production from megakaryocytes, or about the pathogenesis of platelet disorders.
Alessandra Balduini, Alessandra Balduini, Alessandro Malara   +2 more
openaire   +3 more sources

Platelets and Blood Vessels

Journal of Cardiovascular Pharmacology, 1984
The intravascular adhesion and aggregation of platelets initiate hemostasis and arterial thrombosis. In vitro, platelet aggregation is induced by many different agents; which of these is responsible for aggregation in vivo is now under investigation.
openaire   +3 more sources

Antigenicity of Blood Platelets

1969
The first knowledge of the antigenicity of platelets dates from the beginning of this century (Marino, 4905). The authors studied at first the antigenicity in heterorelationship in animals and heteroantibodies, obtained by immunization, were used frequently to provoke experimental thrombopenic purpura. Cole (1907) was the first to prepare a heteroserum
openaire   +3 more sources