Results 71 to 80 of about 184,901 (286)

Blood preservation techniques in complex spine surgery: Illustrative case and review of therapeutic options. [PDF]

Surg Neurol Int, 2021
Caruso JP, Pernik MN, Johnson ZD, El Ahmadieh TY, Ogunnaike B, Adogwa O, Aoun SG, Bagley CA.   +7 more
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

Nature Communications, 2017
The current FDA-approved whole blood stabilization method for circulating tumor cell (CTC) isolation suffers from RNA degradation. Here the authors combine hypothermic preservation and antiplatelet strategies to stabilize whole blood up to 72 h without ...
Keith H. K. Wong, Shannon N. Tessier, David T. Miyamoto, Kathleen L. Miller, Lauren D. Bookstaver, Thomas R. Carey, Cleo J. Stannard, Vishal Thapar, Eric C. Tai, Kevin D. Vo, Erin S. Emmons, Haley M. Pleskow, Rebecca D. Sandlin, Lecia V. Sequist, David T. Ting, Daniel A. Haber, Shyamala Maheswaran, Shannon L. Stott, Mehmet Toner   +18 more
doaj   +1 more source

Critical evaluation of justifications for the transfusion of red blood cells: the reality of a government emergency hospital

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: Blood products and derivatives are indispensable resources in medical therapies. However, it is important to note that the number of donations is far from ideal.
Diego Agra de Souza, Felipe Gama e Silva, Paulo Jose Medeiros de Souza Costa   +2 more
doaj   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Effects of blood storage on ice in biochemical and arterial blood gas analysis of rats Efeitos da estocagem sanguínea em gelo na bioquímica e gasometria arterial de ratos

Acta Cirúrgica Brasileira, 2008
PURPOSE: To investigate the effects of blood storage in biochemical and arterial blood gas analysis of Wistar rats. METHODS: Ten adult male rats with weights between 300-350 g were used.
Marcus Vinicius Henriques Brito, Izabella Cristina Cristo Cunha, Mayra Gonçalves Aragón, Thiago Gabbay Martins Braga, Fabrício Diniz de Lima   +4 more
doaj   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

ERYTHROCYTE PRESERVATION. V. RELATIONSHIP BETWEEN CHEMICAL CHANGES AND VIABILITY OF STORED BLOOD TREATED WITH ADENOSINE 1 [PDF]

, 1955
Beverly W. Gabrio, Dennis M. Donohue, C. A. Finch   +2 more
openalex   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.

PLoS ONE, 2019
Various methods have been devised to dissolve hydrogen gas in organ preservation solutions, including use of a hydrogen gas cylinder, electrolysis, or a hydrogen-generating agent.
Eiji Kobayashi, Motoaki Sano
doaj   +1 more source