Results 51 to 60 of about 1,227,712 (209)
Molecular Genetics and Metabolism Reports, 2020 The rapid progress achieved in the development of many biopharmaceuticals had a tremendous impact on the therapy of many metabolic/genetic disorders. This type of fruitful approach, called protein replacement therapy (PRT), aimed to either replace the ...
Georgios C. Kaiafas +8 more
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CASP3 gene expression and the role of caspase 3 in the pathogenesis of depressive disorders
BMC Psychiatry, 2023 Background The aim of our study was to evaluate the expression of the CASP3 gene at both mRNA and protein levels in patients with depressive disorders and to determine the impact of caspase 3 in the pathogenesis of depression; Methods A total of 290 ...
Katarzyna Bliźniewska-Kowalska +5 more
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Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
, 2017 The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
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Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome
Metabolites, 2019 Most human proteins are glycosylated. Attachment of complex oligosaccharides to the polypeptide part of these proteins is an integral part of their structure and function and plays a central role in many complex disorders.
Karsten Suhre +7 more
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Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. [PDF]
, 2011 The contribution of peripheral immunity to autism spectrum disorders (ASDs) risk is debated and poorly understood. Some mothers of children with ASD have autoantibodies that react to fetal brain proteins, raising the possibility that a subset of ASD ...
Ashwood, P +4 more
core +2 more sources
BIOCHEMICAL PATHWAYS OF METABOLIC DISORDERS IN PSORIASIS
Juvenis Scientia, 2021 The development of metabolic disorders occurs in psoriasis: insulin resistance, systemic inflammation, atherosclerosis, oxidative stress and obesity. The paper presents pathological biochemical pathways of metabolic disorders development which is caused ...
O. V. Samburskaya +2 more
doaj +1 more source
A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. [PDF]
, 2018 BACKGROUND:Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood.
Aschbacher, Kirstin +7 more
core +1 more source
, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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The Serum Pepsinogen Level of Dairy Cows with Gastrointestinal Disorders
İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 2017 The incidence of abomasal mucosal diseases in dairy cows suffering from gastrointestinal disorders is becoming more frequent in modern intensive production. Clinical signs are often non-specific.
Ali HAJIMOHAMMADI +3 more
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Health related effects of wheat varieties [PDF]
, 2020 Summarises the different effects wheat digestion has on human ...
Borgen, Anders
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