Results 101 to 110 of about 505,764 (311)

Analysis of the proteome and the secretome of animal trypanosomes : a standardized analytical method to look for new molecular targets [PDF]

open access: yes, 2007
The causative agents of animal trypanosomosis are various species of protozoan parasites belonging to the genus Trypanosoma, among which T. congolense and T. evansi are the major pathogenic species. The extra cellular position of the trypanosomes implies
Bengaly, Zakaria   +10 more
core  

ELABELA Targets Mitochondria to Modulate Heart Development

open access: yesAdvanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang   +22 more
wiley   +1 more source

Vimentin downregulation is an inherent feature of murine erythropoiesis and occurs independently of lineage [PDF]

open access: yes, 1990
In mammalian erythropoiesis, the mature cells of the primitive lineage remain nucleated while those of the definitive lineage are anuclear. One of the molecular and structural changes that precedes enucleation in cells of the definitive lineage is the ...
Lazarides, Elias   +2 more
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

A retrospective study of the relative utility of electrophoresis in the investigation of serum proteins

open access: yesUniversa Medicina
Background Serum protein electrophoresis (SPE) is widely used for diagnosis, management and monitoring of different immune disorders. Serum protein alterations provide valuable insights about these disorders.
Gusdanis Alberto Campos García   +5 more
doaj   +1 more source

GENETIC VARIATION IN THREE BREEDS OF INDONESIAN LOCAL DUCKS BASED ON BLOOD AND EGG WHITE PROTEIN POLYMORPHISM

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2014
A study of genetic variation of four blood protein loci and three egg white loci in three breeds ofIndonesian local ducks (Magelang duck = MAD, Tegal duck = TED and Mojosari duck= MOD) wasinvestigated by using polyacrilamide gel electrophoresis (PAGE ...
S. Johari, S. Ekasari, E. Kurnianto
doaj   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Green tea extract supplementation ameliorates CCl4-induced hepatic oxidative stress, fibrosis, and acute-phase protein expression in rat

open access: yesJournal of the Formosan Medical Association, 2012
We evaluated the long-term effects of green tea extract (GTE) supplementation on oxidative stress, biliary acute phase protein expression, and liver function in CCl4-induced chronic liver injury.
Guo-Dung Hung   +5 more
doaj   +1 more source

Diagnostic accuracy of urinary prostate protein glycosylation profiling in prostatitis diagnosis [PDF]

open access: yes, 2015
Introduction: Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in
Decaestecker, Karel   +8 more
core   +2 more sources

Home - About - Disclaimer - Privacy