Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19. [PDF]
PLoS Genet, 2022 The COVID-19 pandemic death toll now surpasses two million individuals and there is a need for early identification of individuals at increased risk of mortality.
Palmos AB +10 more
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Hydrolysis Conditions of Porcine Blood Proteins and Antimicrobial Effects of Their Hydrolysates. [PDF]
Food Sci Anim Resour, 2020 In the present study, we determined the degree of hydrolysis (DH) of porcine blood plasma proteins, albumin, and globulin hydrolyzed by six proteases (alcalase, neutrase, flavourzyme, protamex, trypsin, and papain) for various reaction times.
Jin SK, Choi JS, Yim DG.
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The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses. [PDF]
J Pharmacol Exp Ther, 2019 In the blood, depending on their physicochemical characteristics, nanoparticles attract a wide range of plasma biomolecules. The majority of blood biomolecules bind nonspecifically to nanoparticles.
Moghimi SM +4 more
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Networks of blood proteins in the neuroimmunology of schizophrenia. [PDF]
Transl Psychiatry, 2018 Levels of certain circulating cytokines and related immune system molecules are consistently altered in schizophrenia and related disorders. In addition to absolute analyte levels, we sought analytes in correlation networks that could be prognostic.
Jeffries CD +17 more
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Interaction between gold nanoparticles and blood proteins [PDF]
Annals of Medicine, 2021 Introduction Metallic nanoparticles constitute promising biosensing systems, due to their high affinity to biomolecules such as proteins, which form protein coronas of distinct compositions on their surface [1]. Gold nanoparticles (AuNP) are particularly
Carlos Costa +5 more
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Diabetes Care, 2020 OBJECTIVE COVID-19 has become a major public health problem. There is good evidence that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase susceptibility to infection. We aimed to explore risk factors affecting susceptibility to
Rao S, Lau A, So H.
europepmc +3 more sources
The role of basic residues in the adsorption of blood proteins onto the graphene surface. [PDF]
Sci Rep, 2015 With its many unique properties, graphene has shown great potential in various biomedical applications, while its biocompatibility has also attracted growing concerns.
Gu Z +5 more
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Evaluation of silica nanoparticle binding to major human blood proteins. [PDF]
Nanoscale Res Lett, 2014 Nanomaterials are used for various biomedical applications because they are often more effective than conventional materials. Recently, however, it has become clear that the protein corona that forms on the surface of nanomaterials when they make contact
Hata K +7 more
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Control of blood proteins by functional disulfide bonds.
Blood, 2014 Most proteins in nature are chemically modified after they are made to control how, when, and where they function. The 3 core features of proteins are posttranslationally modified: amino acid side chains can be modified, peptide bonds can be cleaved or ...
Butera D +4 more
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The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins [PDF]
BMC Medical Genomics, 2019 Background The conditions of space flight have a significant effect on the physiological processes in the human body, yet the molecular mechanisms driving physiological changes remain unknown.
Daria N. Kashirina +8 more
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