Results 121 to 130 of about 11,143,550 (369)
Genetic control of N-glycosylation of human blood plasma proteins
Вавиловский журнал генетики и селекции, 2023 Glycosylation is an important protein modification, which influences the physical and chemical properties as well as biological function of these proteins.
S. Zh. Sharapov +2 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Simplified Threshold Phenomena in Hypo- and Hyper-coagulation [PDF]
arXiv, 2017 We discuss two threshold phenomena in blood coagulation dynamics using a simplified model. This perspective of the underlying complex phenomena is expected to aid the understanding and characterization of many blood coagulation pathologies with altered protein dynamics.
arxiv
Targeting BCL-2 regulated apoptosis in cancer [PDF]
, 2018 The ability of a cell to undergo mitochondrial apoptosis is governed by pro- and anti-apoptotic members of the BCL-2 protein family. The equilibrium of pro- versus anti-apoptotic BCL-2 proteins ensures appropriate regulation of programmed cell death ...
Campbell, Kirsteen J. +1 more
core +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Persistence of blood paste proteins in a dry white wine after clarification
OENO One, 1999 Until the end of 1997, plasmatic proteins and blood cells could be used to clarify wines. The aim of our work was to study the persistence of these animal proteins in a dry white wine during clarification.
J.-P. Douet +2 more
doaj +1 more source
Optical Marking of Alcohol Induced Hemoglobin Modification [PDF]
arXiv, 2007 It has been shown that conformational modifications of Hb induced by ethanol consumption can be visualized in optical spectra studying oxygenation kinetics of hemoglobin or mixing hemoglobin with Cibacron blue dye. Better dye affinity of blood proteins extracted from alcoholised rats with respect to those from non-alcoholised ones confirms that ethanol
arxiv
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
FEMS Microbiology Reviews, 2016 Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum accounting for the majority of malaria, and P. vivax being a second important cause, especially in Asia, the Americas and the Pacific.
J. Beeson +5 more
semanticscholar +1 more source
Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]
, 2011 Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P. +9 more
core +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source