Results 141 to 150 of about 11,399,320 (390)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Photochemical Consideration in the Interactions between Blood Proteins and Layered Inorganic Materials. [PDF]

Int J Mol Sci, 2022
Yamaguchi T, Kim HM, Oh JM.
europepmc   +1 more source

BLOOD PLASMA PROTEIN PRODUCTION AS INFLUENCED BY VARIOUS DEGREES OF HYPOPROTEINEMIA AND BY AMINO ACIDS [PDF]

, 1941
S. C. Madden, A. P. Turner, A. P. Rowe, G. H. Whipple   +3 more
openalex   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Effect of Hydroalcoholic Extract of Artemisia dracunculus L. (Tarragon) on the Levels of Serum Proteins in Small Laboratory Mice

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: Tarragon (Artemisia dracunculus L.) is a plant, which has nutritional and therapeutic uses for years. In traditional medicine, this plant has been used for relief of indigestion, detoxification of the body, treatment of ...
Mehrdad Modaresi, Mahboobeh Madani, Mahnaz Alasvand Zarasvand   +2 more
doaj  

Application of interpretable machine learning algorithms to predict macroangiopathy risk in Chinese patients with type 2 diabetes mellitus

Scientific Reports
Macrovascular complications are leading causes of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM), yet early diagnosis of cardiovascular disease (CVD) in this population remains clinically challenging.
Ningjie Zhang, Yan Wang, Hui Zhang, Huilong Fang, Xinyi Li, Zhifen Li, Zhenghang Huan, Zugui Zhang, Yongjun Wang, Wei Li, Zheng Gong   +10 more
doaj   +1 more source

The Immune System [PDF]

, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut, McCarthy, Donna O.   +1 more
core   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Identification of salivary gland proteins depleted after blood feeding in the malaria vector Anopheles campestris-like mosquitoes (Diptera: Culicidae).

PLoS ONE, 2014
Malaria sporozoites must invade the salivary glands of mosquitoes for maturation before transmission to vertebrate hosts. The duration of the sporogonic cycle within the mosquitoes ranges from 10 to 21 days depending on the parasite species and ...
Sriwatapron Sor-suwan, Narissara Jariyapan, Sittiruk Roytrakul, Atchara Paemanee, Atchara Phumee, Benjarat Phattanawiboon, Nuchpicha Intakhan, Wetpisit Chanmol, Paul A Bates, Atiporn Saeung, Wej Choochote   +10 more
doaj   +1 more source

Alterations in blood proteins in the prodromal stage of bipolar II disorders. [PDF]

Sci Rep, 2022
Lee H, Han D, Rhee SJ, Kim J, Lee Y, Kim EY, Park DY, Roh S, Baik M, Jung HY, Lee J, Lee TY, Kim M, Shin H, Kim H, Kim SH, Kwon JS, Ahn YM, Ha K.   +18 more
europepmc   +1 more source