Results 151 to 160 of about 11,282,122 (391)

Alterations in blood proteins in the prodromal stage of bipolar II disorders. [PDF]

open access: yesSci Rep, 2022
Lee H   +18 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Measurement of Non-Enzymatic Glycosylated Serum Proteins (GSP) by Improved Thiobarbitoric Acid Assay

open access: yesپزشکی بالینی ابن سینا, 1999
Several classes of protein may undergo non-enzymetic addition of glucose derived product. Hemoglobin was the first protein shown to be modified. Subsequent studies have demonstrated a similar effect of glucose on lens crystalline, collagen, erythrocyte ...
Iraj Khodadadi, Mahin Zahraei
doaj  

Biochemical blood profile and retinol levels in liver broiler chickens with the use of probiotics

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
The use of antibiotics in poultry farming creates a number of risks associated with the development of antibiotic resistance in bacterial disease pathogens. Probiotics are a promising direction for replacing traditional antimicrobial agents.
V. H. Yefimov   +3 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

A genetic correlation scan identifies blood proteins associated with bone mineral density. [PDF]

open access: yesBMC Musculoskelet Disord, 2022
Xu J   +8 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Silica Nanoparticles Effects on Blood Coagulation Proteins and Platelets

open access: yesBiochemistry Research International, 2016
Interaction of nanoparticles with the blood coagulation is important prior to their using as the drug carriers or therapeutic agents. The aim of present work was studying of the primary effects of silica nanoparticles (SiNPs) on haemostasis in vitro.
Volodymyr Gryshchuk, Natalya Galagan
doaj   +1 more source

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