Results 151 to 160 of about 1,343,581 (337)
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
Blood coagulation control proteins.
Nihon Naika Gakkai Zasshi, 1994 血液凝固と凝固制御反応は,正常時における血液の流動性の維持と傷害時における止血と組織修復に不可欠な生体防御反応である.最近の臨床研究により,血栓形成の制御・調節における凝固制御蛋白の重要性が明らかになってきた.凝固制御蛋白の作用機序は多様で, 1)プロテアーゼとして作用して凝固因子を分解する(プロテインC), 2)補酵素蛋白として作用してプロテアーゼの活性を高める(トロンボモジュリン,プロテインS), 3)プロテアーゼインヒビターとして作用して活性化凝固因子を阻害する(アンチトロンビンIII,組織因子系凝固インヒビター)などがある.これらの蛋白は血小板や血管内皮などの細胞膜リン脂質や細胞膜上のヘパリン様物質に結合して活性発現する.本稿では,生理的に重要な凝固制御蛋白の構造と機能の関係 ...
openaire +2 more sources
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Machine Learning of ZnO Interaction with Immunoglobulins and Blood Proteins in Medicine.
J Healthc Eng, 2022 Qader Osman NA +4 more
europepmc +1 more source
AMINO-ACIDS OF THE BLOOD AS THE PRECURSORS OF MILK PROTEINS
, 1920 C. A. Cary
openalex +1 more source
THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD [PDF]
, 1941 Theodore J. Abernethy, Oswald T. Avery
openalex +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Semi‐supervised classification of fundus images combined with CNN and GCN
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose Diabetic retinopathy (DR) is one of the most serious complications of diabetes, which is a kind of fundus lesion with specific changes. Early diagnosis of DR can effectively reduce the visual damage caused by DR. Due to the variety and different morphology of DR lesions, automatic classification of fundus images in mass screening can ...
Sixu Duan +8 more
wiley +1 more source
THE PLASMA PROTEINS IN RELATION TO BLOOD HYDRATION [PDF]
, 1930 Frederick S. Bruckman +2 more
openalex +3 more sources