Results 61 to 70 of about 2,314,484 (362)

TRIM proteins in blood cancers [PDF]

Journal of Cell Communication and Signaling, 2017
Post-translational modification of proteins with ubiquitin plays a central role in regulating numerous cellular processes. E3 ligases determine the specificity of ubiquitination by mediating the transfer of ubiquitin to substrate proteins. The family of tripartite motif (TRIM) proteins make up one of the largest subfamilies of E3 ligases.
Crawford, Lisa J., Johnston, Cliona K., Irvine, Alexandra E.   +2 more
openaire   +4 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Glioblastoma and Blood Microenvironment Predictive Model for Life Expectancy of Patients

Biomedicines
Background: Glioblastoma multiforme (GBM) is a very malignant brain tumor. GBM exhibits cellular and molecular heterogeneity that can be exploited to improve patient outcomes by individually tailoring chemotherapy regimens.
Alexander N. Chernov, Sofia S. Skliar, Mikalai M. Yatskou, Victor V. Skakun, Sarng S. Pyurveev, Ekaterina G. Batotsyrenova, Sergey N. Zheregelya, Guodong Liu, Vadim A. Kashuro, Dmitry O. Ivanov, Sergey D. Ivanov   +10 more
doaj   +1 more source

Water and the Biology of Prions and Plaques [PDF]

, 2007
This is an attempt to account for the insolubility and/or aggregation of prions and plaques in terms of a model of water consisting of an equilibrium between high density and low density microdomains.
Graham K. Steel, Phillippa M. Wiggins
core   +1 more source

Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma [PDF]

, 2016
Serum protein fingerprints associated with MGUS and MM and their changes in MM after autologous stem cell transplantation (MM-ASCT, day 100) remain unexplored.
Fillerová, Regina, Gajdoš, Petr, Kriegová, Eva, Krömer, Pavel, Kudělka, Miloš, Minařík, Jiří, Papajík, Tomáš, Pika, Tomáš, Schneiderová, Petra, Ščudla, Vlastimil   +9 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

GLA PROTEINS – THE WARNING SIGN FOR THE BLOOD VESSELS [PDF]

Journal of IMAB, 2019
The aim of the present work was to perform a critical analysis of the literature related to the role of the extrahepatic matrix Gla-protein (MGP) as an inhibitor of vascular calcification. Online databases PubMed, Google Scholar, Scopus, Science Direct,
Yulian S. Snegarov, Bistra T. Galunska
doaj   +1 more source

Genetic control of N-glycosylation of human blood plasma proteins

Вавиловский журнал генетики и селекции, 2023
Glycosylation is an important protein modification, which influences the physical and chemical properties as well as biological function of these proteins.
S. Zh. Sharapov, A. N. Timoshchuk, Y. S. Aulchenko   +2 more
doaj   +1 more source

Role Of Processed And Natural Cotton On Aedes Aegypti Egg Hatching [PDF]

, 2018
Ae. aegypti is an invasive species and playing a crucial role in disseminating the infectious diseases like dengue and Zika fever. This mosquito, prefers to live in areas close to humans where blood is easily accessible (Powell, et al. 2013).
Drame, Papa, Londono-Renteria, Berlin, Menghwar, Sepna, Montenegro-Cadena, Lidia, Wagner, Ricky   +4 more
core  

Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis [PDF]

, 2014
We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development have been studied, but the results are still controversial.
Barreiro Arcos, María Laura, Cayrol, Maria Florencia, Colombo, L., Cremaschi, Graciela Alicia, Díaz Flaqué, María Celeste, Klecha, Alicia Juana, Martinel Lamas, Diego José, Medina, Vanina Araceli, Paulazo, Maria Alejandra, Sterle, Helena Andrea, Valli, Eduardo   +10 more
core   +1 more source