Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Nature Immunology, 2023 Blood protein extravasation through a disrupted blood–brain barrier and innate immune activation are hallmarks of neurological diseases and emerging therapeutic targets.
Andrew S. Mendiola +20 more
semanticscholar +1 more source
Efficacy of mineral and organic adsorbent in alleviating harmful effects of zearalenone on pig blood serum protein status [PDF]
Veterinarski Glasnik, 2008 The influence of zearalenone on blood serum protein status and the feasibility of utilizing a modified clinoptilolite and esterified glucomannan to alleviate its harmful effects was examined in two trials, 31 and 29 days long, conducted on a total of 64 ...
Nešić Ksenija +2 more
doaj +1 more source
Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]
, 2018 Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro +8 more
core +1 more source
, 2017 Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
core +2 more sources
Clotting Phenomena at the Blood-Polymer Interface and Development of Blood Compatible Polymeric Surfaces [PDF]
, 1972 In the past two decades many attempts have been made to relate surface and interfacial parameters with the blood compatibility of polymeric surfaces. It is however doubtful if by a single parameter the behaviour of blood on a surface can be predicted ...
Bantjes, Adriaan
core +6 more sources
Clinical Proteomics, 2014 Protein biomarkers offer major benefits for diagnosis and monitoring of disease processes. Recent advances in protein mass spectrometry make it feasible to use this very sensitive technology to detect and quantify proteins in blood.
John G. Marshall +3 more
semanticscholar +1 more source
PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease [PDF]
arXiv, 2022 Identification of Alzheimer's Disease (AD)-related transcriptomic signatures from blood is important for early diagnosis of the disease. Deep learning techniques are potent classifiers for AD diagnosis, but most have been unable to identify biomarkers because of their lack of interpretability.
arxiv
Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity [PDF]
, 2018 Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito, when they are ingested in an infectious blood meal. Here, we determine the transmission-reducing activity (TRA) of naturally acquired antibodies from 648 ...
Bousema, Teun +33 more
core +16 more sources
Lipid peroxidation and oxidative protein products in children with episodic fever of unknown origin [PDF]
Journal of Medical Biochemistry, 2014 Background: Episodic fever syndromes are commonly seen in pediatric practice. Episodic fever of unknown origin (FUO) lasts for a few days or weeks and is followed by a fever-free period with a sense of well-being. In this condition, activated neutrophils
Radović Jelena +9 more
doaj
Hepatitis B Virus Protein X Induces Degradation of Talin-1
Viruses, 2016 In the infected human hepatocyte, expression of the hepatitis B virus (HBV) accessory protein X (HBx) is essential to maintain viral replication in vivo.
Maarten A. A. van de Klundert +3 more
doaj +1 more source