Survival of Host Blood Proteins in Ixodes scapularis (Acari: Ixodidae) Ticks: A Time Course Study
Ixodes scapularis Say, 1821 larvae were fed on mice and allowed to molt under laboratory conditions. A liquid chromatography—tandem mass spectrometry-based proteomic study was conducted to identify the type of mammalian proteins present in the derived ...
Ü. A. Laskay+6 more
semanticscholar +1 more source
Terahertz Induced Protein Interactions in a Random Medium [PDF]
Folding of proteins into their correct native structure is key to their function. Simultaneously, the intricate interplay between cell movement and protein conformation highlights the complex nature of cellular processes. In this work, we demonstrate the impact of Terahertz (THz) signaling on controlling protein conformational changes in a random ...
arxiv
The classical central macrophage found in erythroblastic islands plays an important role in erythroblast differentiation, proliferation and enucleation in the bone marrow.
Esther Heideveld+6 more
doaj +1 more source
Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
Chromosome segregation requires the association of the kinetochore protein complex with a specialized nucleosome at the centromere. Here, the authors present cryo-EM and mutational studies that provide insights into the structure of the budding yeast ...
Ruifang Guan+6 more
doaj +1 more source
Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis [PDF]
BACKGROUND: Anopheles gambiae is the main vector of Plasmodium falciparum in Africa. The mosquito midgut constitutes a barrier that the parasite must cross if it is to develop and be transmitted.
Charlwood, J. Derek+6 more
core +11 more sources
Nanosensor dosimetry of mouse blood proteins after exposure to ionizing radiation
Giant magnetoresistive (GMR) nanosensors provide a novel approach for measuring protein concentrations in blood for medical diagnosis. Using an in vivo mouse radiation model, we developed protocols for measuring Flt3 ligand (Flt3lg) and serum amyloid A1 (
Dokyoon Kim+21 more
semanticscholar +1 more source
Early Risk Prediction of Chronic Myeloid Leukemia with Protein Sequences using Machine Learning-based Meta-Ensemble [PDF]
Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist infection effectively.
arxiv
Macromolecular Dynamics in Red Blood Cells Investigated Using Neutron Spectroscopy [PDF]
We present neutron scattering measurements on the dynamics of hemoglobin (Hb) in human red blood cells in vivo. Global and internal Hb dynamics were measured in the ps to ns time- and {\AA} length-scale using quasielastic neutron backscattering spectroscopy. We observed the cross-over from global Hb short-time to long-time self-diffusion.
arxiv +1 more source
Calcium-dependent permeabilization of erythrocytes by a perforin-like protein during egress of malaria parasites. [PDF]
Clinical malaria is associated with proliferation of blood-stage parasites. During the blood stage, Plasmodium parasites invade host red blood cells, multiply, egress and reinvade uninfected red blood cells to continue the life cycle. Here we demonstrate
Chetan E. Chitnis+6 more
core +1 more source
Fully understanding the influence of blood proteins on the assembly structure and dynamics within nanoparticles is difficult because of the complexity of the system and the difficulty in probing the diverse elements and milieus involved. Here we show the
Yuanpei Li+5 more
semanticscholar +1 more source