Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]
, 2010 The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core +1 more source
Analytical and Bioanalytical Chemistry, 2018 The analysis of aggregates of therapeutic proteins is crucial in order to ensure efficacy and patient safety. Typically, the analysis is performed in the finished formulation to ensure that aggregates are not present.
M. Leeman +4 more
semanticscholar +1 more source
Heterogeneity-aware integrative regression for ancestry-specific association studies [PDF]
arXiv, 2023 Ancestry-specific proteome-wide association studies (PWAS) based on genetically predicted protein expression can reveal complex disease etiology specific to certain ancestral groups. These studies require ancestry-specific models for protein expression as a function of SNP genotypes.
arxiv
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery
Cell Reports, 2020 Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases.
Carlos M. Guardia +10 more
doaj
GLA PROTEINS – THE WARNING SIGN FOR THE BLOOD VESSELS [PDF]
Journal of IMAB, 2019 The aim of the present work was to perform a critical analysis of the literature related to the role of the extrahepatic matrix Gla-protein (MGP) as an inhibitor of vascular calcification. Online databases PubMed, Google Scholar, Scopus, Science Direct,
Yulian S. Snegarov, Bistra T. Galunska
doaj +1 more source
Clotting Phenomena at the Blood-Polymer Interface and Development of Blood Compatible Polymeric Surfaces [PDF]
, 1972 In the past two decades many attempts have been made to relate surface and interfacial parameters with the blood compatibility of polymeric surfaces. It is however doubtful if by a single parameter the behaviour of blood on a surface can be predicted ...
Bantjes, Adriaan
core +3 more sources
High contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed Multispectral Optoacoustic Tomography (tuMSOT) [PDF]
, 2014 Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins contrast-to-noise-ratios (CNRs) in optoacoustic imaging. In this way, two variants of the RSFP Dronpa with very similar optoacoustic spectra could be readily discriminated in the ...
arxiv +1 more source
Molecular origin of blood-based infrared fingerprints [PDF]
arXiv, 2021 Previous studies demonstrated that infrared absorption spectra of blood sera may help disease detection. For clinical translation of this approach, it is important to determine the molecular origin of disease-related spectral perturbations. To that end, we supplemented infrared spectroscopy with biochemical fractionation and proteomic profiling, which ...
arxiv
Persistence of blood paste proteins in a dry white wine after clarification
OENO One, 1999 Until the end of 1997, plasmatic proteins and blood cells could be used to clarify wines. The aim of our work was to study the persistence of these animal proteins in a dry white wine during clarification.
J.-P. Douet +2 more
doaj +1 more source
Review: Dystroglycan in the Nervous System [PDF]
, 2007 Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core +2 more sources