Results 71 to 80 of about 6,493,792 (332)

The morphological study of blood vessels in cervical carcinoma (Three-dimensional study by reconstruction models) [PDF]

, 1958
With a view to study the blood vessel construction in cervical cancer the author prepared the reconstruction models and the results to be described below were obtained by three-dimensional observations carried on the models. 1.
Sugihara, Shotaro
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Error propagation analysis of seven partial volume correction algorithms for [18F]THK-5351 brain PET imaging

EJNMMI Physics, 2020
Background Novel partial volume correction (PVC) algorithms have been validated by assuming ideal conditions of image processing; however, in real clinical PET studies, the input datasets include error sources which cause error propagation to the ...
Senri Oyama, Ayumu Hosoi, Masanobu Ibaraki, Colm J. McGinnity, Keisuke Matsubara, Shoichi Watanuki, Hiroshi Watabe, Manabu Tashiro, Miho Shidahara   +8 more
doaj   +1 more source

Pulsatile microvascular blood flow imaging by short-time Fourier transform analysis of ultrafast laser holographic interferometry [PDF]

, 2015
We report on wide-field imaging of pulsatile microvascular blood flow in the exposed cerebral cortex of a mouse by holographic interferometry. We recorded interferograms of laser light backscattered by the tissue, beating against an off-axis reference ...
Atlan, M., Ferezou, I., Fink, M., Paques, M., Puyo, L., Rancillac, A., Sahel, J. A., Simonutti, M.   +7 more
core   +5 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cardiopulmonary Events of the Elderly (≥75 Years) during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan

Medicina
Clazosentan has been shown to prevent vasospasm and reduce mortality in patients after aneurysmal subarachnoid hemorrhage (SAH) and has been approved for clinical use in Japan; however, its systemic events in the elderly (aged ≥ 75 years) have not been ...
Tatsushi Mutoh, Hiroaki Aono, Wataru Seto, Takehiro Kimoto, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa   +6 more
doaj   +1 more source

Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models

, 2019
The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could contribute to our ...
Fang, Linjing, Haft-Javaherian, Mohammad, Muse, Victorine, Nishimura, Nozomi, Sabuncu, Mert R., Schaffer, Chris B.   +5 more
core   +2 more sources

Instability and `Sausage-String' Appearance in Blood Vessels during High Blood Pressure [PDF]

, 1998
A new Rayleigh-type instability is proposed to explain the `sausage-string' pattern of alternating constrictions and dilatations formed in blood vessels under influence of a vasoconstricting agent.
A. E. Green, F. B. Byrom, F. B. Byrom, F. Gustafsson, Finn Gustafsson, J. Giese, J. Giese, J. Plateau, L. J. Beilin, Lord Rayleigh, M. J. Davis, Morten Colding-Jørgensen, Niels-Henrik Holstein-Rathlou, P. Nelson, Preben Alstrøm, R. Bar-Ziv, R. E. Goldstein, R. Feldberg, R. S. Chadwick, R. W. Gore, Victor M. Eguíluz, Y. C. Fung, Y. C. Fung   +22 more
core   +2 more sources

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Nature Communications, 2013
Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan implicated as the primary matrix ...
Vikash P Chauhan, John D. Martin, Hao Liu, D. Lacorre, Saloni R. Jain, S. Kozin, T. Stylianopoulos, A. Mousa, Xiaoxing Han, Pichet Adstamongkonkul, Zoran Popović, P. Huang, M. Bawendi, Y. Boucher, R. Jain   +14 more
semanticscholar   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source