Results 71 to 80 of about 1,235,836 (377)

A deep learning approach to 3D segmentation of brain vasculature [PDF]

, 2019
The segmentation of blood-vessels is an important preprocessing step for the quantitative analysis of brain vasculature. We approach the segmentation task for two-photon brain angiograms using a fully convolutional 3D deep neural network.Published ...
Boas, David, Cheng, Xiaojun, Kura, Sreekanth, Tahir, Waleed, Tian, Lei, Zhu, Jiabei   +5 more
core   +1 more source

Cardiopulmonary Events of the Elderly (≥75 Years) during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan

Medicina
Clazosentan has been shown to prevent vasospasm and reduce mortality in patients after aneurysmal subarachnoid hemorrhage (SAH) and has been approved for clinical use in Japan; however, its systemic events in the elderly (aged ≥ 75 years) have not been ...
Tatsushi Mutoh, Hiroaki Aono, Wataru Seto, Takehiro Kimoto, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa   +6 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

The RETA Benchmark for Retinal Vascular Tree Analysis [PDF]

arXiv, 2021
Topological and geometrical analysis of retinal blood vessel is a cost-effective way for early detection of many common diseases. Meanwhile, automated vessel segmentation and vascular tree analysis are still lacking in terms of generalization capability. In this work, we construct a novel benchmark RETA with 81 labeled vessel masks aiming to facilitate
arxiv  

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Diffusion MRI Fiber Tractography and Benzodiazepine SPECT Imaging for Assessing Neural Damage to the Language Centers in an Elderly Patient after Successful Reperfusion Therapy

Geriatrics
Background: Intravenous thrombolysis and mechanical thrombectomy are the first-line reperfusion therapies for acute ischemic stroke. Here, we describe the utility of diffusion magnetic resonance imaging (MRI) fiber tractography and 123I-iomazenil ...
Tatsushi Mutoh, Yasuyuki Yoshida, Yasuko Tatewaki, Hongkun Chin, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa   +6 more
doaj   +1 more source

U-Net with Graph Based Smoothing Regularizer for Small Vessel Segmentation on Fundus Image [PDF]

ICONIP2019, 2020
The detection of retinal blood vessels, especially the changes of small vessel condition is the most important indicator to identify the vascular network of the human body. Existing techniques focused mainly on shape of the large vessels, which is not appropriate for the disconnected small and isolated vessels.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Phenotypic spectrum of the first Belgian MYBPC3 founder: a large multi-exon deletion with a varying phenotype

Frontiers in Genetics
BackgroundVariants in the MYBPC3 gene are a frequent cause of hypertrophic cardiomyopathy (HCM) but display a large phenotypic heterogeneity. Founder mutations are often believed to be more benign as they prevailed despite potential negative selection ...
Hanne M. Boen, Hanne M. Boen, Maaike Alaerts, Lut Van Laer, Johan B. Saenen, Johan B. Saenen, Inge Goovaerts, Inge Goovaerts, Jarl Bastianen, Pieter Koopman, Philippe Vanduynhoven, Elke De Vuyst, Michael Rosseel, Hein Heidbuchel, Hein Heidbuchel, Emeline M. Van Craenenbroeck, Emeline M. Van Craenenbroeck, Bart Loeys   +17 more
doaj   +1 more source

CURRENT METHODS OF OUTPATIENT ELECTROCARDIOGRAPHIC MONITORING. CLINICAL ASPECTS

Klinicist, 2017
The review presents the clinical characteristics and comparative data of application of modern non-invasive and invasive methods of ambulatory electrocardiographic monitoring in the diagnosis of arrhythmias and cardiac conduction.
E. V. Pervova
doaj   +1 more source