Results 91 to 100 of about 331,507 (304)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

ENURESIS IN ADOLESCENTS AND CONSCRIPTS: MODERN APPROACHES TO DIAGNOSTICS

Педиатрическая фармакология, 2014
The article lists results of a complex examination of adolescents and conscripts of 15–23 years of age with enuresis performed according to the Ulyanovsk Region military commissariat’s referral in 2003–2012.
A. L. Malykh, I. N. Zakharova, M. I. Pykov   +2 more
doaj   +1 more source

Comparison of Different Analytical Methods for the Determination of Carbon Monoxide in Postmortem Blood

, 2020
The determination of carbon monoxide (CO) and carboxyhemoglobin (COHb) is of utmost importance in forensic toxicology to determine the cause of death in cases of CO poisoning, fire, and explosions. To this end, reliable and updated analytical methods are
Zanaboni M., Dei Cas M., Gambaro V., Casagni E., Roda G., Arnoldi S.   +5 more
core   +1 more source

Synthesis and characterization of size-selective nanoporous polymeric adsorbents for blood purification. [PDF]

, 2009
Crosslinked polystyrene co-divinylbenzene adsorbent microspheres with median diameters between 40 and 300 μm, with an enhanced proportion of mesopores in the range 4–10 nm, have been synthesized using a membrane emulsification technique.
Trochimczuk, Andrzej W., D.J. Malik, Malik, Danish Javed, Chris Webb (7127804), R.G. Holdich, C. Webb, Dale, James A., Iain Roche (7127942), G.L. Warwick, N.A. Hoenich (7128515), G.L. Warwick (7128506), Danish Malik (1254321), Richard Holdich (1253271), J.J. Ramsden (7128503), J.A. Dale (7128512), David Williams (1248024), Warwick, Graham L., Roche, I., Holdich, Richard G., I. Roche, Williams, David John, J.A. Dale, A.W. Trochimczuk, N.A. Hoenich, J.J. Ramsden, D.J. Williams, Hoenich, Nicholas Andrew, Webb, C., Ramsden, Jeremy J., Andrzej W. Trochimczuk (7128509)   +29 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Modeling the sampling volume for the skin blood oxygenation measurements [PDF]

, 2001
The absolute quantified measurement of haemoglobin skin blood saturation from collected reflectance spectra of the skin is complicated by the fact that the blood content of tissues can vary both in the spatial distribution and in the amount.
Meglinski, I. V., Matcher, S. J.
core  

Capillary Electrophoresis with Capacitively Coupled Contactless Conductivity Detection for Quantitative Analysis of Dried Blood Spots with Unknown Blood Volume

, 2019
Blood volume in dried blood spot (DBS) analysis is assumed to be constant for DBS punches with a fixed area. However, blood volume in the punch is dependent on several factors associated with the blood composition and is preferentially normalized by off ...
Lenka Ryšavá (8138559), Miloš Dvořák (8138556), Pavel Kubáň (4276759)   +2 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Red blood cell distribution width as a prognostic marker of mortality in patients on chronic dialysis: a single center, prospective longitudinal study

, 2013
Aim To determine if red cell distribution width (RDW) is associated with all-cause mortality in patients on chronic dialysis and to evaluate its prognostic value among validated prognostic biomarkers.
Vladimira Vuletić, Romić, Željko, Lovorka Đerek, Đerek, Lovorka, Željko Romić, Pehar, Mario, Boris Starčević, Mario Pehar, Velimir Božikov, Starčević, Boris, Božikov, Velimir, Sičaja, Mario, Mario Sičaja, Vuletić, Vladimira   +13 more
core   +1 more source