Results 71 to 80 of about 331,507 (304)

CHANGES OF BLOOD CYTOKINE LEVELS IN THE COURSE OF DEVELOPING LIVER INSUFFICIENCY AFTER HEPATIC SURGERY

Медицинская иммунология, 2014
. The study was carried out in the patients with bulky masses in the liver. Acute hepatic failure was initiated by resection of the liver. In the patients with bulky masses in the liver, increased serum levels of the common cytokines were detected during
A. N. Plekhanov, S. P. Chikoteev, F. I. Tovarshinov, N. I. Soboleva   +3 more
doaj   +1 more source

Investigation of the relationship between phenylalanine in venous plasma and capillary blood using volumetric blood collection devices

JIMD Reports, 2023
Measurement of plasma and dried blood spot (DBS) phenylalanine (Phe) is key to monitoring patients with phenylketonuria (PKU). The relationship between plasma and capillary DBS Phe concentrations has been investigated previously, however, differences in ...
Rachel S. Carling, Zoe Barclay, Nathan Cantley, Erin C. Emmett, Sarah L. Hogg, Yael Finezilber, Danja Schulenburg‐Brand, Elaine Murphy, Stuart J. Moat   +8 more
doaj   +1 more source

Methodology of True Pulmonary Blood Volume Determination [PDF]

Circulation, 1966
"True" pulmonary blood volume has been determined by three indicator-dilution methods in 96 subjects. In two methods a right or left ventricular mixing chamber is interposed between the injection and sampling sites while in the third such a mixing chamber is absent.
P, Samet, W H, Bernstein, A, Lopez, S, Levine   +3 more
openaire   +2 more sources

Methods to assess iron and iodine status

, 2008
Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin.
Zimmermann, Michael B., Zimmermann, M.B.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The impact of maternal protein restriction during rat pregnancy upon renal expression of angiotensin receptors and vasopressin-related aquaporins

Reproductive Biology and Endocrinology, 2010
Background Maternal protein restriction during rat pregnancy is known to impact upon fetal development, growth and risk of disease in later life. It is of interest to understand how protein undernutrition influences the normal maternal adaptation to ...
Cornock Ruth, Langley-Evans Simon C, Mobasheri Ali, McMullen Sarah   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Analysis of albumin Raman scattering registration efficiency from different volume and shape cuvette

Journal of Biomedical Photonics & Engineering, 2017
The cuvette shape influence on the Raman registration efficiency at small volumes of albumin (0.15-1 ml) using the PLS model was analysed. This paper examines the smallest measurement error RMSE of 3-6 g/l with a correlation coefficient R2 = 0.95 was ...
Anastasia A. Lykina, Dmitry N. Artemyev, Ivan A. Bratchenko   +2 more
doaj   +1 more source

The pathophysiology of fluid removal during haemodialysis: implications for blood volume monitoring and determination of dry weight.

, 2007
The aim of the research was to characterise the pathophysiology of ultrafiltration (UF) during haemodialysis (HD) using a range of assessment tools. The hypothesis was that objective monitoring would facilitate accurate estimation of dry weight (DW) and ...
Mitra, S., Mitra, Sandip
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source