Results 71 to 80 of about 899,662 (357)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

CHANGES OF BLOOD CYTOKINE LEVELS IN THE COURSE OF DEVELOPING LIVER INSUFFICIENCY AFTER HEPATIC SURGERY

Медицинская иммунология, 2014
. The study was carried out in the patients with bulky masses in the liver. Acute hepatic failure was initiated by resection of the liver. In the patients with bulky masses in the liver, increased serum levels of the common cytokines were detected during
A. N. Plekhanov, S. P. Chikoteev, F. I. Tovarshinov, N. I. Soboleva   +3 more
doaj   +1 more source

Pairwise hydrodynamic interactions and diffusion in a vesicle suspension [PDF]

, 2014
The hydrodynamic interaction of two deformable vesicles in shear flow induces a net displacement, in most cases an increase of their distance in the transverse direction.
Coupier, Gwennou, Gires, Pierre-Yves, Misbah, Chaouqi, Podgorski, Thomas, Srivastav, Aparna   +4 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The impact of maternal protein restriction during rat pregnancy upon renal expression of angiotensin receptors and vasopressin-related aquaporins

Reproductive Biology and Endocrinology, 2010
Background Maternal protein restriction during rat pregnancy is known to impact upon fetal development, growth and risk of disease in later life. It is of interest to understand how protein undernutrition influences the normal maternal adaptation to ...
Cornock Ruth, Langley-Evans Simon C, Mobasheri Ali, McMullen Sarah   +3 more
doaj   +1 more source

The effects of Montmorency tart cherry juice supplementation and FATMAX exercise on fat oxidation rates and cardio-metabolic markers in healthy humans [PDF]

, 2018
Montmorency tart cherries (Prunus cerasus L.) are rich in anthocyanins, compounds capable of augmenting fat oxidation and regulating metabolic dysfunction.
Bottoms, Lindsay, Desai, Terun, Roberts, Michael   +2 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Analysis of albumin Raman scattering registration efficiency from different volume and shape cuvette

Journal of Biomedical Photonics & Engineering, 2017
The cuvette shape influence on the Raman registration efficiency at small volumes of albumin (0.15-1 ml) using the PLS model was analysed. This paper examines the smallest measurement error RMSE of 3-6 g/l with a correlation coefficient R2 = 0.95 was ...
Anastasia A. Lykina, Dmitry N. Artemyev, Ivan A. Bratchenko   +2 more
doaj   +1 more source

Investigation of the relationship between phenylalanine in venous plasma and capillary blood using volumetric blood collection devices

JIMD Reports, 2023
Measurement of plasma and dried blood spot (DBS) phenylalanine (Phe) is key to monitoring patients with phenylketonuria (PKU). The relationship between plasma and capillary DBS Phe concentrations has been investigated previously, however, differences in ...
Rachel S. Carling, Zoe Barclay, Nathan Cantley, Erin C. Emmett, Sarah L. Hogg, Yael Finezilber, Danja Schulenburg‐Brand, Elaine Murphy, Stuart J. Moat   +8 more
doaj   +1 more source

Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury or Vaccines Containing Thimerosal [PDF]

, 2005
Thimerosal is a preservative that has been used in manufacturing vaccines since the 1930s. Reports have indicated that infants can receive ethylmercury (in the form of thimerosal) at or above the U.S.
Burbacher, Thomas M., Cernichiari, Elsa, Clarkson, Thomas, Grant, Kimberly S., Liberato, Noelle, Shen, Danny D.   +5 more
core   +2 more sources