Results 41 to 50 of about 1,441,912 (353)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Le Tumulus d'Apatesaro V (Compte rendu de fouilles 1985). [PDF]
Munibe Antropologia-Arkeologia, 1988 El túmulo pedregoso, de Apatesaro V, excavado en Julio de 1985 mide 7 m. de diámetro y 0.50 m. de altura, sin estructura particular. Es un amontonamiento de piedras sin ningún orden, con un depósito de carbón vegetal en el centro. No se ha hallado ningún
Jacques Blot
doaj
A Ponceau S Staining-Based Dot Blot Assay for Rapid Protein Quantification of Biological Samples
Gels, 2022 Despite the availability of a wide range of commercial kits, protein quantification is often unreliable, especially for tissue-derived samples, leading to uneven loading in subsequent experiments. Here we show that the widely used Bicinchoninic Acid (BCA)
Dario Lucas Helbing +4 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Munibe Antropologia-Arkeologia, 1998 El círculo de piedras Mendizabal 7, de 8 metros de diámetro, presenta una corona externa constituida de grandes bloques hincados en la tierra, y otra interna y tangente, de elementos idénticos sólo puestos en el suelo. El cajón central está compuesto
Jacques Blot
doaj
Lucille Ball, the Queen of Show Business versus Lucy Ricardo, the Failed Actress
Transatlantica, 2011 Most American people, all generations taken into account, remember Lucille Ball as a great comic figure of the Fifties. Nonetheless, just a few people remember her as one of the most powerful women of her time.
Aurélie Blot
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Le tumulus d'Apatesaro IV (Compte - rendu de fouille). [PDF]
Munibe Antropologia-Arkeologia, 1984 Se da cuenta de los resultados obtenidos en la excavación del túmulo de Apatesaro IV, describiendo su arquitectura y reconstruyendo su rito funerario.
Jacques Blot
doaj
A Defined Methodology for Reliable Quantification of Western Blot Data
Molecular Biotechnology, 2013 Chemiluminescent western blotting has been in common practice for over three decades, but its use as a quantitative method for measuring the relative expression of the target proteins is still debatable.
Sean C. Taylor +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source