Results 201 to 210 of about 98,102 (238)

From Everyman to Hamlet: A Distant Reading

open access: yesRenaissance Studies, EarlyView.
Abstract The sixteenth century sees English drama move from Everyman to Hamlet: from religious to secular subject matter and from personified abstractions to characters bearing proper names. Most modern scholarship has explained this transformation in terms originating in the work of Jacob Burckhardt: concern with religion and a taste for ...
Vladimir Brljak
wiley   +1 more source

Screening of different species reveals cat hepatocytes support HBV infection. [PDF]

open access: yesPLoS Pathog
Xu Z   +12 more
europepmc   +1 more source

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima   +14 more
wiley   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

open access: yesExperimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal   +9 more
wiley   +1 more source

Discovery of Viroids and Viroid‐Like RNAs in Plants

open access: yes
Plant Biotechnology Journal, EarlyView.
Zhiyou Xuan   +15 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

open access: yesExperimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene   +4 more
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted   +11 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

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