Results 31 to 40 of about 12,984 (208)

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors [PDF]

, 2020
Genomic instability can be a hallmark of both human genetic disease and cancer. We identify a deleterious UBQLN4 mutation in families with an autosomal recessive syndrome reminiscent of genome instability disorders.
Beleggia, Filippo, Bustos, Matias A., Checa Rodríguez, Cintia, Goergens, Jonas, Huertas Sánchez, Pablo, Isensee, Jörg, Jachimowicz, Ron D., Velpula, Bhagya Bhavana   +7 more
core   +1 more source

Cerebriform intradermal nevus presenting as cutis verticis gyrata with multiple cellular blue nevus over the body: A rare occurrence

Indian Dermatology Online Journal, 2014
Cutis verticis gyrata is a rare skin condition characterized by swelling of scalp resembling the surface of the brain. Various conditions, like cerebriform intradermal nevus (CIN), may give rise to this clinical entity.
Somenath Sarkar, Soumyajit Roychoudhury, Arpit Shrimal, Kapildeb Das   +3 more
doaj   +1 more source

Zosteriform speckled lentiginous nevus with bilateral segmental neurofibromatosis: A rare association

Pigment International, 2021
Bilateral segmental neurofibromatosis is a nonfamilial variant of neurofibromatosis without any systemic involvement. Speckled lentiginous nevus (SLN) is a pigmented, light brown to tan patch of varied diameter, speckled with smaller, darker colored ...
Bhagyashree B Supekar, Vaishali H Wankhade, Apoorva D Chopkar, Rajesh P Singh, Dharitri Bhat   +4 more
doaj   +1 more source

BRAF wild-type melanoma in situ arising in a BRAF V600E mutant dysplastic nevus [PDF]

, 2015
IMPORTANCE The BRAF V600E mutation accounts for the majority of BRAF mutations found in cutaneous melanoma and is also commonly found in nevi. We used dermoscopy-targeted sampling and a microbiopsy device coupled with DNA sequence analysis to highlight ...
Flewell-Smith, Ross, Jagirdar, Kasturee, Lambie, Duncan, Lin, Lynlee L., Prow, Tari W., Schaider, Helmut, Soyer, H. Peter, Sturm, Richard A., Tan, Jean-Marie   +8 more
core   +1 more source

Comparative dermatology: blue nevus [PDF]

Anais Brasileiros de Dermatologia, 2012
There are elements in nature that may be compared to some dermatological lesions, such as the black pearl, which is very similar to a cellular blue nevus observed in the gluteus region of a 31-year-old male patient.
Barros, Jefferson Alfredo de, Kafler, Cristiane Calcidoni, Barros, Juliano Cesar de, Proto, Rodrigo Sestito, Priscila dos Santos, Costa, Machado Filho, Carlos D'Apparecida   +5 more
openaire   +4 more sources

Optical Coherence Tomography Angiography of Iris Nevus: A Case Report [PDF]

, 2016
Iris nevus is common: 6% of patients with suspected iris melanoma have lesions other than melanoma, and 36% of them are nevi. Iris nevus turns into melanoma in approximately 8% of cases at a mean of 15 years.
Allegrini, D., Montesano, G., Pece, A.
core   +3 more sources

Blue nevus with a starburst pattern on dermoscopy

Dermatology Practical & Conceptual, 2012
An 11-year-old girl presented to our department with a blue-gray papule approximately 4 mm in diameter. We suspected that it was a blue nevus or a pigmented Reed/Spitz nevus.
Takeo Shiga, Kimiko Nakajima, Masahito Tarutani, Miki Izumi, Masaru Tanaka, Shigetoshi Sano   +5 more
doaj   +1 more source

Metastatic melanoma with features of blue nevus and tumoral melanosis identified during pembrolizumab therapy

JAAD Case Reports, 2017
Metastatic melanoma may exhibit clinical or histologic features of blue nevus. Pembrolizumab therapy is associated with regression and tumoral melanosis.
Matthew F. Helm, MD, Michael J. Bax, MD, Paul N. Bogner, MD, Catherine G. Chung, MD   +3 more
doaj   +1 more source

Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]

, 2014
BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Arozarena, Imanol, Erice, O., Ferguson, J., Goicoechea, I., Margison, G.P., Wellbrock, C.   +5 more
core   +2 more sources

Genetics of melanoma progression: the rise and fall of cell senescence. [PDF]

, 2016
There are many links between cell senescence and the genetics of melanoma, meaning both familial susceptibility and somatic-genetic changes in sporadic melanoma.
Al-Khalaf, Albino, Alimonti, Alonso, Anders, Aoude, Aoude, Artandi, Bandyopadhyay, Bandyopadhyay, Barrett, Bartkova, Bastian, Bastian, Bataille, Bell, Ben-Porath, Bennett, Bennett, Bennett, Berger, Bevona, Bond, Boyle, Cairney, Campisi, Cao, Carvajal, Carvalho, Chandler, Chen, Chien, Christensen, Chudnovsky, Clark, Conde-Perez, Coppé, Coppé, Corre, Curtin, Curtin, Cust, Dankort, Delmas, DePinho, Dhomen, Ding, Dono, Easty, Forbes, Freund, Fujimoto, Fung, Garrido, Gembarska, Gisselsson, Glaessl, Goldstein, Gray-Schopfer, Griewank, Gruis, Ha, Ha, Hanahan, Hayflick, Heaphy, Helgadottir, Herbig, Herbig, Hewitt, Hodis, Hoek, Horn, Huang, Hurk, Hussussian, Iles, Jacobs, Jacobs, Jeck, Johmura, Jönsson, Kraehn, Krauthammer, Krauthammer, Kuilman, Kuilman, Lade-Keller, Lam, Laoukili, Lawrence, Lin, Lin, Londono-Vallejo, MacKenzie Ross, Martínez, Michaloglou, Mooi, Moore, Muñoz-Espín, Nagel, Nan, Narita, Newton-Bishop, Nogueira, Ogbah, Ohanna, Overhoff, Passos, Patton, Pavey, Pawlikowski, Petti, Poliakov, Pollock, Prickett, Reddel, Ressler, Rhee, Robert, Robles-Espinoza, Rode, Rossiello, Rovillain, Ruas, Ruhe, Salama, Sargen, Sato, Serrano, Shay, Shi, Shitara, Snoo, Soengas, Soo, Stark, Stefanaki, Stratton, Straume, Suram, Sviderskaya, Sviderskaya, Sviderskaya, The Cancer Genome Atlas Network, Topping, Tran, Treszl, Tsao, Von Zglinicki, Vredeveld, Wansleben, Wellbrock, Wen, Widmer, Worm, Xia, Xiong, Zhang, Zhu   +159 more
core   +1 more source