Results 101 to 110 of about 1,319,206 (306)

The green, blue and grey water footprint of farm animals and animal products [PDF]

, 2010
The projected increase in the production and consumption of animal products is likely to put further pressure on the globe’s freshwater resources. The size and characteristics of the water footprint vary across animal types and production systems.
Hoekstra, Arjen Ysbert, Hoekstra, A.Y., Mekonnen, M.M., Hoekstra, Arjen Y., Mekonnen, Mesfin, Mekonnen, Mesfin M.   +5 more
core   +1 more source

Biofuel scenarios in a water perspective: The global blue and green water footprint of road transport in 2030 [PDF]

, 2012
Concerns over energy security and climate change stimulate developments towards renewable energy. Transport is expected to switch from fossil fuel use to the use of fuel mixtures with a larger fraction of biofuels, e.g. bio-ethanol and biodiesel. Growing
van Lienden, A.R., Hoekstra, A.Y., van der Meer, Th.H., Gerbens-Leenes, P.W.   +3 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Evaluating Country-Scale Irrigation Demand Through Parsimonious Agro-Hydrological Modeling

Hydrology
Climate change is expected to reduce water availability during cropping season, while growing populations and rising living standards will increase the global water demand. This creates an urgent need for national water management tools to optimize water
Nike Chiesa Turiano, Marta Tuninetti, Francesco Laio, Luca Ridolfi   +3 more
doaj   +1 more source

Transboundary water governance institutional architecture: reflections from Ethiopia and Sudan [PDF]

Transboundary water resource governance is premised on equitable water and water-related benefit sharing. Using the case of the Blue Nile (Ethiopia and Sudan), we explore the conceptual issues that need consideration in the crafting of cross-border ...
Tafesse, T., Awulachew, Seleshi Bekele, Mapedza, Everisto, Haileslassie, A., McCartney, Matthew, Hagos, Fitsum   +5 more
core  

Sustainable and efficient allocation of limited blue and green water resources [PDF]

, 2018
Freshwater stems from precipitation over land, which differentiates into a blue water flow (groundwater and surface water) and a green water flow (evaporation).
Schyns, Joseph Franciscus
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Water storage in an era of climate change: addressing the challenge of increasing rainfall variability. Blue paper [PDF]

Water storage / Climate change / Rain / Dams ...
McCartney, Matthew, Smakhtin, Vladimir
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Water footprints of irrigated crops in the Chirakchi Watershed, Uzbekistan

Frontiers in Agronomy
The water footprint of crops (WFP) is crucial to understand how efficiently water is used in a farming system. This study evaluated the green and blue water footprints of selected crops in the Chirakchi Watershed, located in southern Uzbekistan.
Abeyou W. Worqlul, Akmal Akramkhanov, Zafar Gafurov   +2 more
doaj   +1 more source