Results 41 to 50 of about 66,089 (294)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Effect of enzyme preparation on quality of preserves in flavored oil from poorly maturing fish of the North Basin [PDF]

Vestnik MGTU, 2016
The paper considers the need for developing new technologies for processing poorly maturing fish of the North Basin based on the analysis of catch volumes and taking into account the main directions of state policy of development of the fishing industry.
Brazhnaya I. E.
doaj   +1 more source

Report on the Diet of the Blue Whiting in the Barents Sea in the Summer 2005 and in the Winters of 2002 and 2006 [PDF]

, 2006
We analyzed stomach content of blue whiting in the Barents Sea in February-March 2002 and 2006, and in August-September 2005. Krill was the most important prey for blue whiting in the Barents Sea, and constituted about 90% of diet in winter and 50% in ...
Beck, I.M., Eriksen, K.B., Heino, M., Johannesen, E., Olsen, E.M.   +4 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A High-Speed Fish Evisceration System (FES) for Bycatch and Underutilized Fish Stocks [PDF]

, 2012
Development of a high-speed and high-yield water-powered fish evisceration system (FES) to efficiently preprocess small fish and bycatch for producing minced fish meat is described.
Babbitt, Jerry K., Barnett, Harold, Nicklason, Peter M.   +2 more
core  

Changes in the structure and functionof the North Sea fish foodweb, 1973-2000, and the impacts of fishing and climate [PDF]

, 2005
North Sea environmental and biological data were analysed to examine 30-year changes in production and consumption in the fish food web. The analysis revealed that the demand for secondary production placed on the ecosystem by fish declined from ...
Beare, Beaugrand, Broekhuizen, Bryant, Christensen, Clark, Clark, Collie, Daan, Daan, Dugdale, Duineveld, Edwards, Fogarty, Fox, Frid, Garrison, Greenstreet, Greenstreet, Hay, Heip, Hirtzler, Huntley, Jennings, Jobling, Jonas, Jones, Jones, McKay, McKay, Michael R. Heath, Murawski, Pauly, Pauly, Pauly, Pielou, Pope, Pyper, Reid, Rice, Richardson, Richardson, Richardson, Runge, Sparholt, Steele, Tasker, Zwanenburg   +47 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Water-Soluble Fish Protein Intake Led to Lower Serum and Liver Cholesterol Concentrations in Obese Zucker fa/fa Rats

Marine Drugs, 2018
Proteins from different fish species and different raw materials such as fish fillets and by-products have shown promising cardioprotective effects in rodents and humans, including effects on cholesterol metabolism. Blue whiting is used mainly to produce
Aslaug Drotningsvik, Linn Anja Vikøren, Svein Are Mjøs, Åge Oterhals, Daniela Pampanin, Ola Flesland, Oddrun Anita Gudbrandsen   +6 more
doaj   +1 more source