Results 51 to 60 of about 66,089 (294)

Choosing the observational likelihood in state-space stock assessment models

, 2016
Data used in stock assessment models result from combinations of biological, ecological, fishery, and sampling processes. Since different types of errors propagate through these processes it can be difficult to identify a particular family of ...
Albertsen, Christoffer Moesgaard, Nielsen, Anders, Thygesen, Uffe Høgsbro   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Regional variability in the trophic requirements of shelf sea fisheries in the Northeast Atlantic, 1973-2000 [PDF]

, 2005
Hydrographic, plankton, benthos, fisheries landings, and fish diet data from shelf sea areas in the Northeast Atlantic have been combined into an analysis of the foodweb structure and secondary production requirements of regional fisheries. Fish landings
Baretta-Bekker, Beare, Beaugrand, Beaugrand, Broekhuizen, Christensen, deYoung, Duineveld, Ebenhöh, Edwards, Greenstreet, Heath, Heip, Huntley, Jones, Jones, Michael R. Heath, Murawski, Pauly, Pauly, Reid, Sparholt, Steele   +22 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Accelerated motion and the self-force in Schwarzschild spacetime [PDF]

, 2018
We provide expansions of the Detweiler-Whiting singular field for motion along arbitrary, planar accelerated trajectories in Schwarzschild spacetime. We transcribe these results into mode-sum regularization parameters, computing previously unknown terms ...
Diener, Peter, Heffernan, Anna, Ottewill, Adrian C., Warburton, Niels, Wardell, Barry   +4 more
core   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bioenergetics modeling of the annual consumption of zooplankton by pelagic fish feeding in the Northeast Atlantic.

PLoS ONE, 2018
The present study uses bioenergetics modeling to estimate the annual consumption of the main zooplankton groups by some of the most commercially important planktivorous fish stocks in the Northeast Atlantic, namely Norwegian spring-spawning (NSS) herring
Eneko Bachiller, Kjell Rong Utne, Teunis Jansen, Geir Huse   +3 more
doaj   +1 more source

Black Hole Mass Estimates of Radio Selected Quasars

, 2002
The black hole (BH) mass in the centre of AGN has been estimated for a sample of radio-selected flat-spectrum quasars to investigate the relationship between BH mass and radio properties of quasars. We have used the virial assumption with measurements of
A. Y. K. N. Oshlack, Drinkwater M. J., Francis P. J., Kormendy J., M. T. Whiting, R. L. Webster, Wilkes B. J.   +6 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source