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Bovine leukemia virus (BLV) is an important cattle pathogen that causes major economic losses worldwide, especially in dairy farms. The use of animal models provides valuable insight into the pathogenesis of viral infections. Experimental infections of sheep have been conducted using blood from BLV-infected cattle, infectious BLV molecular clones or ...
Irène Alvarez +2 more
exaly +5 more sources
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Amperometric immunosensor for diagnosis of BLV infection
Biosensors and Bioelectronics, 2008A new amperometric immunosensor for detection of antibodies against bovine leukemia protein (gp51) was designed. The detection of antibody-antigen complex formation was based on application of secondary antibodies labeled with horseradish peroxidase (HRP). Ferrocenecarboxylic acid (FCA) and N,N,N',N'-tetramethylbenzidine (TMB) were selected as suitable
Almira Ramanaviciene +2 more
exaly +3 more sources
Veterinary Microbiology
Bovine leukemia virus (BLV) is a widespread virus that decreases milk production and quality in dairy cows. As crucial components of BLV, BLV-encoded microRNAs (BLV-miRNAs) affect BLV replication and may impact the synthesis of Lactoferrin (LTF), Lactoperoxidase (LPO), Alpha-lactalbumin (alpha-LA), and Beta-lactoglobulin (beta-LG).
Shuai Lian
exaly +3 more sources
Bovine leukemia virus (BLV) is a widespread virus that decreases milk production and quality in dairy cows. As crucial components of BLV, BLV-encoded microRNAs (BLV-miRNAs) affect BLV replication and may impact the synthesis of Lactoferrin (LTF), Lactoperoxidase (LPO), Alpha-lactalbumin (alpha-LA), and Beta-lactoglobulin (beta-LG).
Shuai Lian
exaly +3 more sources
Elicitation of bovine antibody to BLV-gp51 by BLV-vaccination.
Leukemia, 1989This study was carried out to demonstrate sequential changes of antibody response to gp51 of BLV in bovine hosts injected with BLV-vaccine. BLV vaccine was prepared from culture fluids from FLK-BLV cells by treatment with 0.1% formalin for 48 hrs at 4 degrees C followed by ultrafiltration and lyophilization. Sterile vaccine containing 300 mg protein/ml,
K, Maruyama +6 more
openaire +1 more source
Journal of Veterinary Medicine, Series B, 1996
The mechanism of BLV-induced tumorigenesis has not been clear up to now. Changes of viral protein expression in infected cells may be involved in the molecular events leading to BLV-induced leukaemogenesis. In this study Western blot investigations of cells transfected with plasmid DNA containing the complete Japanese BLV tumour clone provirus ...
P, Blankenstein +4 more
openaire +2 more sources
The mechanism of BLV-induced tumorigenesis has not been clear up to now. Changes of viral protein expression in infected cells may be involved in the molecular events leading to BLV-induced leukaemogenesis. In this study Western blot investigations of cells transfected with plasmid DNA containing the complete Japanese BLV tumour clone provirus ...
P, Blankenstein +4 more
openaire +2 more sources
Microbiology and Immunology, 1992
AbstractLymphocyte proliferation responses were investigated in sheep and cattle, in which the replication of bovine leukemia virus (BLV) had been known to be suppressed by inoculation with recombinant vaccinia virus (rVV) expressing BLV envelope glycoprotein (gp60).
K, Ohishi +8 more
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AbstractLymphocyte proliferation responses were investigated in sheep and cattle, in which the replication of bovine leukemia virus (BLV) had been known to be suppressed by inoculation with recombinant vaccinia virus (rVV) expressing BLV envelope glycoprotein (gp60).
K, Ohishi +8 more
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The BLV-induced leukemia-lymphosarcoma complex in sheep
Veterinary Immunology and Immunopathology, 1989Sheep are highly susceptible to BLV infection and can be infected via several different means (routes). In all inoculated animals, specific anti-BLV antibodies can be demonstrated 1 to 3 months post-inoculation (p.i.). Between 10 and 13 months p.i., a moderate but persistent lymphocytosis (PL) may be detected in about 50% of the infected animals.
S, Djilali, A L, Parodi
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Berliner und Munchener tierarztliche Wochenschrift, 1998
A typical infection with bovine leukemia virus (BLV) induces a permanent antibody (Ab) response with high titers against BLV-antigens. In the last few years atypical courses of infection with low or transient BLV-Ab-titers or even lack of any detectable BLV-Ab-titers in animals with BLV-provirus integration have been described.
P, Blankenstein +5 more
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A typical infection with bovine leukemia virus (BLV) induces a permanent antibody (Ab) response with high titers against BLV-antigens. In the last few years atypical courses of infection with low or transient BLV-Ab-titers or even lack of any detectable BLV-Ab-titers in animals with BLV-provirus integration have been described.
P, Blankenstein +5 more
openaire +1 more source
2019
???????????????? ???????????????????? ?????????????????????????? (????) ???? ?????????????????? ?? LTR BLV (?????????? 341??? 616 ??. ??.) ?? ???????? X BLV (?????????? 6497???7929 ??. ??.) ?????????????????????????????????????? ?? ???????????? ???????????? ?????? ???????????? FLK, ???????????????????????? ?????????????????????????? BLV. ???????????????
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???????????????? ???????????????????? ?????????????????????????? (????) ???? ?????????????????? ?? LTR BLV (?????????? 341??? 616 ??. ??.) ?? ???????? X BLV (?????????? 6497???7929 ??. ??.) ?????????????????????????????????????? ?? ???????????? ???????????? ?????? ???????????? FLK, ???????????????????????? ?????????????????????????? BLV. ???????????????
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BLV proviral DNA in the genome of the target lymphocyte.
Archiv fur Geschwulstforschung, 1980info:eu-repo/semantics ...
Kettmann, Richard +3 more
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