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Multi-omics study and ncRNA regulation of anti-BmNPV in silkworms, Bombyx mori: an update [PDF]

Frontiers in Microbiology, 2023
Bombyx mori silkworm is an important economic insect which has a significant contribution to the improvement of the economy. Bombyx mori nucleopolyhedrovirus (BmNPV) is a vitally significant purulent virus that impedes the sustainable and stable ...
Yi-Xuan Fan, Vivian Andoh, Liang Chen
doaj   +5 more sources

Bombyx mori Ecdysone Receptor B1 May Inhibit BmNPV Infection by Triggering Apoptosis [PDF]

Insects, 2023
Bombyx mori nucleopolyhedrovirus (BmNPV) is a serious threat to sericulture. Nevertheless, no effective control strategy is currently available. The innate immunity of silkworm is critical in the antiviral process.
Zhihao Su, Chunxiao Zhao, Xinming Huang, Junli Lv, Ziqin Zhao, Kaiyi Zheng, Xia Sun, Sheng Qin, Xueyang Wang, Byung-Rae Jin, Yangchun Wu   +10 more
doaj   +5 more sources

Complete genome determination of a European <i>Bombyx mori</i> nucleopolyhedrovirus (BmNPV) strain isolated in the French Cevennes. [PDF]

Microbiol Resour Announc
The Bombyx mori nucleopolyhedrovirus (BmNPV) is a critical pathogen in sericulture; yet, it also holds great promise for the bioproduction of recombinant proteins.
Loizel C, Grébert T.
europepmc   +3 more sources

Bombyx mori RPL12 Participates in UV-Induced DNA Damage Repair and Interacts with BmNPV Bm65 Protein Only After Ultraviolet Radiation. [PDF]

Insects
Simple Summary Because of environmental pollution, solar ultraviolet radiation is increasing day by day and typically causes DNA damage. Here, we found that a Bombyx mori ribosomal protein RPL12 is indirectly involved in UV-induced DNA damage repair ...
Tang Q, Chen C, Huang J, Li G, Zhu F, Yu Q, Sun L, Chen H, Chen L, Ma S, Liu X, Chen K.   +11 more
europepmc   +4 more sources

The mortality of Bombyx mori larvae challenged by BmNPV is reduced when supplemented with Lactobacillus acidophilus bacteria [PDF]

BMC Research Notes
Objective Bombyx mori nucleopolyhedrovirus (BmNPV) causes grasserie with severe effects in Thai strains of the silkworm Bombyx mori. The aim of this study was to investigate the effect of probiotic supplementation on the survival of silkworm larvae ...
Siripuk Suraporn, Vallaya Suthikhum, Olle Terenius   +2 more
doaj   +3 more sources

BmNPV interacts with super-enhancer regions of the host chromatin to hijack cellular transcription machinery. [PDF]

Nucleic Acids Res
Effective transcriptional activation relies on the spatial interaction between specific DNA elements. DNA interactions have also been observed between DNA viruses and their hosts, with limited understanding of the involved details.
Zhao S, Wang X, Yang T, Zhu X, Wu X.
europepmc   +2 more sources

Functional analysis of <i>BmTsp.C</i> in modulating infection of BmNPV through apoptosis pathways in domestic silkworm (<i>Bombyx mori</i>). [PDF]

J Gen Virol
The silkworm, Bombyx mori, is a crucial model insect in agriculture and biological research. Tetraspanins, known for their effects in regulating cellular functions like cell signalling, adhesion, migration and diffusion, take on a crucial role in viral ...
Xu Y, Wei Y, Zhang J, Zhang D, Zhao Q, Shen D.   +5 more
europepmc   +2 more sources

Baculovirus enhances arginine uptake and induces mitochondrial autophagy to promote viral proliferation. [PDF]

PLoS Pathogens
As obligatory intracellular parasites, viruses must rely on metabolic reprogramming of host cells to meet their replication needs. Baculovirus is an important biopesticide and a vector for the preparation of biological products.
Shigang Fei, Junming Xia, Yigui Huang, Minyang Zhou, Biying Xie, Yibing Kong, Luc Swevers, Jingchen Sun, Min Feng   +8 more
doaj   +2 more sources

The signal peptide of BmNPV GP64 activates the ERAD pathway to regulate heterogeneous secretory protein expression. [PDF]

Microb Cell Fact
As a powerful eukaryotic expression vector, the baculovirus expression vector system (BEVS) is widely applied to the production of heterogeneous proteins for research and pharmaceutical purposes, while optimization of BEVS remains a work in progress for ...
Liu N, Xu Y, Sun L, Li M, Huang J, Hao B.   +5 more
europepmc   +2 more sources

Transcriptome Dynamics of BmN Cells During the Early Phase of Bombyx mori Nucleopolyhedrovirus Infection [PDF]

Insects
The silkworm, Bombyx mori, is an economically important insect severely impacted by Bombyx mori nucleopolyhedrovirus (BmNPV), a double-stranded DNA virus that causes substantial losses to the sericulture industry.
Xiong Wang, Fangyu Miao, Wei Wang, Jingchen Sun, Lunguang Yao   +4 more
doaj   +2 more sources