Results 21 to 30 of about 2,161 (218)

Bacterial pigments: A colorful palette reservoir for biotechnological applications

Biotechnology and Applied Biochemistry, Volume 69, Issue 3, Page 981-1001, June 2022., 2022
Abstract Synthetic derivatives are currently used instead of pigments in many applicative fields, from food to feed, from pharmaceutical to diagnostic, from agronomy to industry. Progress in organic chemistry allowed to obtain rather cheap compounds covering the whole color spectrum. However, several concerns arise from this chemical approach, as it is
Viviana Teresa Orlandi, Eleonora Martegani, Cristina Giaroni, Andreina Baj, Fabrizio Bolognese   +4 more
wiley   +1 more source

Comparative Transcriptome Analysis of Bombyx mori (Lepidoptera) Larval Midgut Response to BmNPV in Susceptible and Near-Isogenic Resistant Strains. [PDF]

PLoS ONE, 2016
Bombyx mori nucleopolyhedrovirus (BmNPV) is one of the primary pathogens causing severe economic losses in sericulture. However, the molecular mechanism of silkworm resistance to BmNPV remains largely unknown.
Xue-Yang Wang, Hai-Zhong Yu, Lei Geng, Jia-Ping Xu, Dong Yu, Shang-Zhi Zhang, Yan Ma, Dong-Qiong Fei   +7 more
doaj   +1 more source

Two Cholesterol Recognition Amino Acid Consensus Motifs of GP64 with Uncleaved Signal Peptide Are Required for Bombyx mori Nucleopolyhedrovirus Infection

Microbiology Spectrum, 2021
The signal peptide (SP) of integrated membrane proteins is removed cotranslationally or posttranslationally in the endoplasmic reticulum, while GP64, a membrane fusion protein of Bombyx mori nucleopolyhedrovirus (BmNPV), retains its SP in the mature ...
Bifang Hao, Wenbin Nan, Ying Xu, Lin Liu, Na Liu, Jinshan Huang   +5 more
doaj   +1 more source

RNA N6‐methyladenosine modification suppresses replication of rice black streaked dwarf virus and is associated with virus persistence in its insect vector

Molecular Plant Pathology, Volume 22, Issue 9, Page 1070-1081, September 2021., 2021
N6 methylation of adenosine modification might be the epigenetic mechanism that regulates rice black streaked dwarf virus replication in its insect vector and maintains a certain virus threshold for persistent transmission. Abstract N6 methylation of adenosine (m6A) was recently discovered to play a role in regulating the life cycle of various viruses ...
Shuping Tian, Nan Wu, Lu Zhang, Xifeng Wang   +3 more
wiley   +1 more source

CRISPR/Cas9-Mediated Disruption of the lef8 and lef9 to Inhibit Nucleopolyhedrovirus Replication in Silkworms

Viruses, 2022
Bombyx mori nucleopolyhedrovirus (BmNPV) is a pathogen that causes severe disease in silkworms. In a previous study, we demonstrated that by using the CRISPR/Cas9 system to disrupt the BmNPV ie-1 and me53 genes, transgenic silkworms showed resistance to ...
Yujia Liu, Xiaoqian Zhang, Dongbin Chen, Dehong Yang, Chenxu Zhu, Linmeng Tang, Xu Yang, Yaohui Wang, Xingyu Luo, Manli Wang, Yongping Huang, Zhihong Hu, Zulian Liu   +12 more
doaj   +1 more source

CRISPR/Cas12a Mediated Genome Editing Enhances Bombyx mori Resistance to BmNPV [PDF]

Frontiers in Bioengineering and Biotechnology, 2020
CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCas12a has been developed for insect genome editing, and the novel Cas12a orthologs nucleases and editing efficiency require more study on insects.
Zhanqi Dong, Qi Qin, Zhigang Hu, Xinling Zhang, Jianghao Miao, Liang Huang, Peng Chen, Cheng Lu, Cheng Lu, Minhui Pan, Minhui Pan   +10 more
openaire   +3 more sources

Overexpression Bombyx mori HEXIM1 Facilitates Immune Escape of Bombyx mori Nucleopolyhedrovirus by Suppressing BmRelish-Driven Immune Responses

Viruses, 2022
Bombyx mori nucleopolyhedrovirus (BmNPV), a typical arthropod-specific enveloped DNA virus, is one of the most serious pathogens in silkworm farming, but the potential mechanisms of the evasion of innate immune responses from BmNPV infection are still ...
Guanping Chen, Yuedong Li, Xiangshuo Kong, Shudi Zhao, Jiale Li, Xiaofeng Wu   +5 more
doaj   +1 more source

Knockdown of BmTCP-1β Delays BmNPV Infection in vitro [PDF]

Frontiers in Microbiology, 2019
The molecular mechanism of silkworm resistance to Bombyx mori nucleopolyhedrovirus (BmNPV) infection remains unclear. The chaperonin containing t-complex polypeptide 1 (TCP-1) is essential for the folding of tubulin and actin to produce stable and functional competent protein conformation. However, little is known about this protein in silkworm. In the
Xue-yang Wang, Xue-yang Wang, Zuo-min Shao, Qian-ying Chen, Jia-ping Xu, Xia Sun, Xia Sun, Zhen-ping Xu, Zhen-ping Xu, Mu-wang Li, Mu-wang Li, Yang-chun Wu, Yang-chun Wu   +12 more
openaire   +3 more sources

Phenotypic grouping of 141 BmNPVs lacking viral gene sequences [PDF]

Virus Research, 2012
We constructed a series of gene knockout BmNPVs (KOVs) for each of 141 genes (Gomi et al., 1999; Katsuma et al., 2011) using the BmNPV T3 bacmid system (Ono et al., 2007) and lambda red recombination system (Datsenko and Wanner, 2000). In a subsequent analysis of the properties needed for infection using a marker gene, egfp (enhanced green fluorescent ...
Ono, Chikako, Kamagata, Takanori, Taka, Hitomi, Sahara, Ken, Asano, Shin-ichiro, Bando, Hisanori   +5 more
openaire   +3 more sources

Silkworm expression system as a platform technology in life science [PDF]

, 2009
Many recombinant proteins have been successfully produced in silkworm larvae or pupae and used for academic and industrial purposes. Several recombinant proteins produced by silkworms have already been commercialized.
00397366, 2907, 2907, 2910, 2910, 4521, 4522, 4d68973e-f6ff-4d7d-9439-c121d8831040, 90238246, bd6a76a9-51e0-42ce-9e57-130004af2bc5, Kajikawa, Mizuho, Kato, Tatsuya, Maenaka, Katsumi, Park, Enoch Y.   +13 more
core   +2 more sources