Results 41 to 50 of about 1,113 (177)

Gene Expression Pattern and Regulatory Network of α‐Toxin Treatment in Bombyx mori

International Journal of Genomics, Volume 2019, Issue 1, 2019., 2019
Bacillus bombyseptieus is a pathogen of Bombyx mori; it can cause bacterial septicemia in silkworm. One of the components of the parasporal crystal toxin of B. bombyseptieus, α‐toxin, plays an important role in the process of infection in silkworm. In this study, we investigated the immune response of silkworm induced by α‐toxin by using RNA‐seq.
Tieshan Feng, Ping Lin, Jiao Gong, Dong Cheng, Xi Yang, Quan Zhang, Tingcai Cheng, Luigi Ceci   +7 more
wiley   +1 more source

Transcriptomic Analysis of Resistant and Susceptible Bombyx mori Strains Following BmNPV Infection Provides Insights into the Antiviral Mechanisms

International Journal of Genomics, Volume 2016, Issue 1, 2016., 2016
Purpose. To decipher transcriptomic changes and related genes with potential functions against Bombyx mori nucleopolyhedrovirus infection and to increase the understanding of the enhanced virus resistance of silkworm on the transcriptomic level. Methods.
Gang Li, Heying Qian, Xufang Luo, Pingzhen Xu, Jianhua Yang, Mingzhu Liu, Anying Xu, Kristina M. Herbert   +7 more
wiley   +1 more source

Bombyx mori Ecdysone Receptor B1 May Inhibit BmNPV Infection by Triggering Apoptosis

Insects, 2023
Bombyx mori nucleopolyhedrovirus (BmNPV) is a serious threat to sericulture. Nevertheless, no effective control strategy is currently available. The innate immunity of silkworm is critical in the antiviral process.
Zhihao Su, Chunxiao Zhao, Xinming Huang, Junli Lv, Ziqin Zhao, Kaiyi Zheng, Xia Sun, Sheng Qin, Xueyang Wang, Byung-Rae Jin, Yangchun Wu   +10 more
doaj   +1 more source

The Expression, Purification, and Characterization of a Ras Oncogene (Bras2) in Silkworm (Bombyx mori)

International Journal of Genomics, Volume 2013, Issue 1, 2013., 2013
The Ras oncogene of silkworm pupae (Bras2) may belong to the Ras superfamily. It shares 77% of its amino acid identity with teratocarcinoma oncogene 21 (TC21) related ras viral oncogene homolog‐2 (R‐Ras2) and possesses an identical core effector region. The mRNA of Bombyx mori Bras2 has 1412 bp. The open reading frame contains 603 bp, which encodes 200
Zhengbing Lv, Tao Wang, Wenhua Zhuang, Dan Wang, Jian Chen, Zuoming Nie, Lili Liu, Wenping Zhang, Lisha Wang, Deming Wang, Xiangfu Wu, Jun Li, Lian Qian, Yaozhou Zhang, Graziano Pesole   +14 more
wiley   +1 more source

Use of Bacterial Artificial Chromosomes in Baculovirus Research and Recombinant Protein Expression: Current Trends and Future Perspectives

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
The baculovirus expression system is one of the most successful and widely used eukaryotic protein expression methods. This short review will summarise the role of bacterial artificial chromosomes (BACS) as an enabling technology for the modification of the virus genome. For many years baculovirus genomes have been maintained in E.
Polly Roy, Rob Noad, M. Feiss, P. D. Ghiringhelli, T. Krishnan   +4 more
wiley   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Protection against Autoimmune Diabetes by Silkworm‐Produced GFP‐Tagged CTB‐Insulin Fusion Protein

Journal of Immunology Research, Volume 2011, Issue 1, 2011., 2011
In animals, oral administration of the cholera toxin B (CTB) subunit conjugated to the autoantigen insulin enhances the specific immune‐unresponsive state. This is called oral tolerance and is capable of suppressing autoimmune type 1 diabetes (T1D).
Qiaohong Meng, Wenfeng Wang, Xiaowen Shi, Yongfeng Jin, Yaozhou Zhang, Nick Giannoukakis   +5 more
wiley   +1 more source

A hypothetical model of crossing Bombyx mori nucleopolyhedrovirus through its host midgut physical barrier.

PLoS ONE, 2014
Bombyx mori nucleopolyhedrovirus (BmNPV) is a primary pathogen of silkworm (B. mori) that causes severe economic losses each year. However, the molecular mechanisms of silkworm-BmNPV interactions, especially the silkworm proteins that can interact with ...
Yang Cheng, Xue-Yang Wang, Hao Hu, Nabil Killiny, Jia-Ping Xu   +4 more
doaj   +1 more source

Influence of BmNPV orf98 on DNA replication, transcription and virus package of Bombyx mori nucleopolyhedrovirus

浙江大学学报. 农业与生命科学版, 2015
Baculoviruses have been considered as the powerful vectors to express the exogenous gene. And the representative vectors in baculovirus expression vector system is Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV) and Bombyx mori ...
Shi Lili, Jiang Caiying, Yu Wei, Chen Chen, Jiang Lei, Gong Chengjian, Tong Fudan   +6 more
doaj   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source