Results 11 to 20 of about 3,948 (257)

Pathogenicity Detection and Genome Analysis of Two Different Geographic Strains of BmNPV [PDF]

Insects, 2021
The pathogenicity of different concentrations of Bombyx mori nuclear polyhedrosis virus- Zhenjiang strain (BmNPV ZJ) and Yunnan strain (BmNPV YN) was assessed in Baiyu larvae.
Huimin Guo, Benzheng Zhang, Xin Zheng, Juan Sun, Huiduo Guo, Gang Li, Guodong Zhao, Anying Xu, Heying Qian   +8 more
doaj   +5 more sources

Genome-wide chromatin interaction profiling reveals a vital role of super-enhancers and rearrangements in host enhancer contacts during BmNPV infection. [PDF]

Genome Res, 2023
As influential regulatory elements in the genome, enhancers control gene expression under specific cellular conditions, and such connections are dynamic under different conditions.
Zhao S, Li Y, Chen G, Wang X, Chen N, Wu X.   +5 more
europepmc   +4 more sources

Unraveling dual fusion mechanisms in BmNPV GP64: critical roles of CARC motifs and signal peptide retention. [PDF]

J Virol
Viral membrane fusion is a critical process enabling viruses to invade host cells, driven by viral membrane fusion proteins (MFPs). Cholesterol plays a pivotal role in this process, which is essential for the infectivity of many enveloped viruses.
Sun L, Xu Y, Chen K, Nan W, Wang M, Zhang Y, Hao B, Huang J.   +7 more
europepmc   +3 more sources

BmREEPa Is a Novel Gene that Facilitates BmNPV Entry into Silkworm Cells.

PLoS ONE, 2015
We previously established two silkworm cell lines, BmN-SWU1 and BmN-SWU2, from Bombyx mori ovaries. BmN-SWU1 cells are susceptible while BmN-SWU2 cells are highly resistant to BmNPV infection. Interestingly, we found that the entry of BmNPV into BmN-SWU2
Xiao-long Dong, Tai-hang Liu, Wei Wang, Cai-xia Pan, Yun-fei Wu, Guo-yu Du, Peng Chen, Cheng Lu, Min-hui Pan   +8 more
doaj   +4 more sources

Transcriptomic Analysis of Resistant and Susceptible Bombyx mori Strains Following BmNPV Infection Provides Insights into the Antiviral Mechanisms [PDF]

International Journal of Genomics, Volume 2016, Issue 1, 2016., 2016
Purpose. To decipher transcriptomic changes and related genes with potential functions against Bombyx mori nucleopolyhedrovirus infection and to increase the understanding of the enhanced virus resistance of silkworm on the transcriptomic level. Methods.
Gang Li, Heying Qian, Xufang Luo, Pingzhen Xu, Jianhua Yang, Mingzhu Liu, Anying Xu, Kristina M. Herbert   +7 more
wiley   +2 more sources

The NPC Families Mediate BmNPV Entry

Microbiology Spectrum, 2022
Baculovirus is an important biological factor for controlling insect populations and represents a powerful biological tool for gene delivery and expression. However, the host receptor of baculovirus is still unknown.
Youpeng Fan, Jialing Bao, Xiaoyu Fu, Pengfei Wu, Jingya Chen, Yan Huang, Junhong Wei, Guoqing Pan, Chunfeng Li, Zeyang Zhou   +9 more
openaire   +4 more sources

SUMOylation Regulates BmNPV Replication by Moderating PKIP Intracellular Localization [PDF]

Processes, 2022
SUMOylation is a reversible covalent process between a small ubiquitin-like modifier (SUMO) and its target protein and has become a crucial regulator of protein functions. Here, we report that Bombyx mori nucleopolyhedrovirus (BmNPV) may take advantage of the host SUMOylation system to enhance its own replication, similar to many other viruses.
Rui Shen, Dingding Lü, Guanyu Chen, Mengjin Liu, Shiqi Pu, Yiling Zhang, Qiang Wang, Ping Qian, Xudong Tang   +8 more
openaire   +3 more sources

DNA methylomes and transcriptomes analysis reveal implication of host DNA methylation machinery in BmNPV proliferation in Bombyx mori [PDF]

BMC Genomics, 2019
Background Bombyx mori nucleopolyhedrosis virus (BmNPV) is a major pathogen that threatens the sustainability of the sericultural industry. DNA methylation is a widespread gene regulation mode in epigenetics, which plays an important role in host immune ...
Haoling Huang, Ping Wu, Shaolun Zhang, Qi Shang, Haotong Yin, Qirui Hou, Jinbo Zhong, Xijie Guo   +7 more
doaj   +2 more sources

The Bmtret1 Gene Family and Its Potential Role in Response to BmNPV Stress in Bombyx mori. [PDF]

Int J Mol Sci, 2023
Trehalose is a non-reducing disaccharide and participates in physiological activities such as organ formation, energy metabolism, and stress resistance in insects. The Bmtret1 gene family is mainly involved in in the sugar metabolism of silkworm.
Lin M, Qian Y, Chen E, Wang M, Ouyang G, Xu Y, Zhao G, Qian H.   +7 more
europepmc   +2 more sources

Immobilization of foreign protein into polyhedra of Bombyx mori nucleopolyhedrovirus (BmNPV) [PDF]

Journal of Zhejiang University SCIENCE B, 2012
In the late phase of Bombyx mori nucleopolyhedrovirus (BmNPV) infection, a large amount of polyhedra appear in the infected cell nucleolus, these polyhedra being dense protein crystals protecting the incorporated virions from the harsh environment.
Xing-wei, Xiang, Rui, Yang, Lin, Chen, Xiao-long, Hu, Shao-fang, Yu, Cui-ping, Cao, Xiao-feng, Wu   +6 more
openaire   +4 more sources