Results 181 to 190 of about 52,292 (275)

Overexpression of Bmp4 induces microphthalmia by disrupting embryonic neural retina

Neurobiology of Disease
Microphthalmia, mostly an autosomal dominant disorder, is a worldwide severe congenital ocular malformation that causes visual impairment. Our investigation unveiled a total of 30 genes associated with microphthalmia.
Baige Li, Zeyuan Pu, Keren Liao, Yuxin Du, Gao Tan, Scott Nawy, Shiqiang Gao, Yin Shen   +7 more
doaj   +1 more source

A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration [PDF]

, 2004
Previous work has revealed that proteins that bind to bone morphogenetic proteins (BMPs) and inhibit their signalling have a crucial role in the spatial and temporal regulation of cell differentiation and cell migration by BMPs.
Bronner-Fraser, Marianne, Christiansen, Jeff, Coles, Edward, Economou, Androulla, Wilkinson, David G.   +4 more
core  

Genetic Landscape of Robin Sequence: A Systematic Review

Clinical Genetics, Volume 109, Issue 2, Page 218-232, February 2026.
This systematic review summarizes the genetic landscape of Robin sequence (RS), highlighting key differences between isolated and non‐isolated forms and emphasizing the role of up‐to‐date genetic testing for diagnosis and clinical management. ABSTRACT Robin sequence (RS) is a congenital condition characterized by micrognathia, glossoptosis, and upper ...
Shirley van de Velde, Aebele B. Mink van der Molen, Augusta M. A. Lachmeijer, Daan de Leijer, Jeroen J. Smits, Maarten P. G. Massink, Sarah L. Versnel, Marie‐José H. van den Boogaard, Emma C. Paes   +8 more
wiley   +1 more source

Designing signaling environments to steer transcriptional diversity in neural progenitor cell populations [PDF]

, 2019
Stem cell populations within developing embryos are diverse, composed of many different subpopulations of cells with varying developmental potential. The structure of stem cell populations in cell culture remains poorly understood and presents a barrier ...
Chen, Sisi, Park, Jong H., Rivaud, Paul, Thomson, Matt, Tsou, Tiffany   +4 more
core  

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. [PDF]

, 2019
Organogenesis involves integration of diverse cell types; dysregulation of cell-type-specific gene networks results in birth defects, which affect 5% of live births.
de Soysa, T Yvanka, Del Sol, Antonio, Gifford, Casey A, Huang, Yu, Okawa, Satoshi, Ranade, Sanjeev S, Ravichandran, Srikanth, Salunga, Hazel T, Schricker, Amelia, Srivastava, Deepak   +9 more
core  

BMP4 Gene [PDF]

, 2020
openaire   +1 more source

Bone morphogenetic protein 4 (BMP4) [PDF]

Science-Business eXchange, 2011
openaire   +3 more sources

BMP4 wt Allele [PDF]

, 2020
openaire   +1 more source

Muscle-Derived BMP4 Regulates Morphology and Function of Endplates on Extrafusal and Intrafusal Muscle Fibers in Adult Mice. [PDF]

J Neurosci
Harrison JM, Podor B, Yans A, Rafuse VF.
europepmc   +1 more source

Amelioration of polycystic ovarian morphology by Tokishakuyakusan in a PCOS rat model: association with bone morphogenetic protein 4. [PDF]

Front Endocrinol (Lausanne)
Ueda M, Osuka S, Yabuki A, Miyake N, Fujitsuka N, Nahata M, Tokita Y, Ruan J, Bayasula, Takeda T, Seki T, Sonehara R, Muraoka A, Nakamura T, Kajiyama H.   +14 more
europepmc   +1 more source