Results 1 to 10 of about 75,583 (111)

The serum levels of activin A and bone morphogenetic protein-4 and -6 in patients with fibrodysplasia ossificans progressiva [PDF]

Orphanet Journal of Rare Diseases, 2023
Background Fibrodysplasia ossificans progressiva (FOP) is an ultrarare and disabling genetic disorder of connective tissue characterized by congenital malformation of the great toes, and progressive heterotopic ossification (HO) in soft connective ...
Zhengqin Ye, Siyi Wang, Chang Shan, Qi Zhu, Ying Xue, Keqin Zhang   +5 more
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Bone morphogenetic protein 4 alleviates nonalcoholic steatohepatitis by inhibiting hepatic ferroptosis [PDF]

Cell Death Discovery, 2022
Nonalcoholic steatohepatitis (NASH) is a state of simple steatosis that progresses to inflammation and liver injury accompanied by ferroptosis. Bone morphogenetic protein 4 (BMP4) plays an important role in adipogenesis and differentiation, as well as in
Xingchun Wang, Bingwei Ma, Xin Wen, Hui You, Chunjun Sheng, Le Bu, Shen Qu   +6 more
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Bone morphogenetic protein 4 in perivascular adipose tissue ameliorates hypertension through regulation of angiotensinogen [PDF]

Frontiers in Cardiovascular Medicine, 2022
BackgroundPerivascular adipose tissue (PVAT), an active endocrine organ, exerts direct effect on vascular tone through paracrine. Activation of PVAT metabolism plays an inhibitory role in atherosclerosis via secreting relaxing factors.
Wen-Juan Mu, Yan-Jue Song, Li-Jie Yang, Shu-Wen Qian, Qi-Qi Yang, Yang Liu, Qi-Qun Tang, Yan Tang   +7 more
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The Role of Bone Morphogenetic Protein 4 in Microglial Polarization in the Process of Neuropathic Pain [PDF]

Journal of Inflammation Research, 2022
Changqing Liu,1,2,* Qi Sun,1,2,* Junmei Xu,1,2 Weiyun Shen,1,2 Hui Li,1,2 Lin Yang1,2 1Department of Anesthesiology, Second Xiangya Hospital, Central South University, Changsha, Hunan Province, People’s Republic of China; 2Hunan Province Center ...
Liu C, Sun Q, Xu J, Shen W, Li H, Yang L
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Platelet Bone Morphogenetic Protein-4 Mediates Vascular Inflammation and Neointima Formation after Arterial Injury [PDF]

Cells, 2021
The purpose of this study is to investigate the role of platelet bone morphogenetic proteins (BMP)-4 during vascular inflammation and remodeling in a mouse model of carotid wire injury. Transgenic mice with a platelet-specific deletion of BMP-4 (BMP4Plt−/
Marietta Jank, Nikolaus von Niessen, Christoph B. Olivier, Hannah Schmitt, Nathaly Anto-Michel, Ingo Hilgendorf, Christoph Bode, Martin Moser, Jennifer S. Esser, Qian Zhou   +9 more
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Bone Morphogenetic Protein 4 Alleviates DSS-Induced Ulcerative Colitis Through Activating Intestinal Stem Cell by Target ID3 [PDF]

Frontiers in Cell and Developmental Biology, 2021
Damage to intestinal epithelial cell proliferation or intestinal stem cell (ISC) maintenance may trigger inflammatory bowel disease (IBD), and protecting the ISCs is critical for IBD treatment.
Lei Hu, Lei Hu, Lei Hu, Lei Hu, Junji Xu, Junji Xu, Junji Xu, Junji Xu, Xue Wang, Xue Wang, Liang Feng, Liang Feng, Chunmei Zhang, Chunmei Zhang, Chunmei Zhang, Jinsong Wang, Jinsong Wang, Songlin Wang, Songlin Wang, Songlin Wang   +19 more
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Correction: Bone morphogenetic protein 4 alleviates nonalcoholic steatohepatitis by inhibiting hepatic ferroptosis [PDF]

Cell Death Discovery, 2022
Xingchun Wang, Bingwei Ma, Xin Wen, Hui You, Chunjun Sheng, Le Bu, Shen Qu   +6 more
doaj   +2 more sources

Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4 [PDF]

Heliyon, 2020
Matrix Gla protein (MGP), a modulator of the BMP-SMAD signals, inhibits arterial calcification in a Glu γ-carboxylation dependent manner but the role of MGP highly expressed in a subset of bone marrow (BM) mesenchymal stem/stromal cells is unknown.
Kana Kuronuma, Aya Yokoi, Tomoya Fukuoka, Muneaki Miyata, Akio Maekawa, Satowa Tanaka, Leo Matsubara, Chie Goto, Miki Matsuo, Hao-Wei Han, Mai Tsuruta, Haruka Murata, Hikari Okamoto, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito   +15 more
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Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone [PDF]

JBMR Plus, 2020
Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation.
Marita Westhrin, Toril Holien, Muhammad Zahoor, Siv Helen Moen, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D deBruijn, Anton Martens, Richard WJ Groen, Fatima Bosch, Ulf Smith, Anne‐Marit Sponaas, Anders Sundan, Therese Standal   +15 more
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Assessment of serum levels of bone morphogenetic proteins as sensitive biomarkers for early prediction of acute myocardial infarction. [PDF]

Egyptian Journal of Pure and Applied Science, 2023
Although acute myocardial infarction (AMI) is a life-threatening disease, rapid diagnosis may reduce mortality risk. Despite being highly specific for AMI, cardiac troponin I (cTnI) does not distinguish between the etiologically diverse of myocardial ...
Fahmy Ali, Nahla Hassan, Rehab Abdrabouh, Samia Hasssan, Mostafa Elnozahi, Ahmed Soliman   +5 more
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