Results 41 to 50 of about 88,042,096 (284)

New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it

open access: yesLipids in Health and Disease, 2017
Background Bone morphogenetic protein 4 (BMP-4) has been proven to regulate white adipogensis. We aimed to demonstrate the correlation of BMP-4 with fat distribution and Exenatide treatment on it. Methods We enrolled 69 obese patients. Anthropometric and
Xingchun Wang   +7 more
doaj   +1 more source

Expression of human bone morphogenetic protein (BMP-2 and BMP-4) genes in transgenic bovine fibroblasts Expressão dos genes bone morphogenetic protein (BMP-2 e BMP-4) em fibroblastos bovinos transgênicos

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
cDNAs dos genes bone morphogenetic protein-2 (BMP-2) e bone morphogenetic protein-4 (BMP-4) foram sintetizados a partir de RNA total extraído de tecidos ósseos de pacientes que apresentavam trauma facial (fraturas do maxilar entre o 7º e o 10º dia pós ...
C. Oleskovicz   +2 more
doaj   +1 more source

Novel fluorescent probes for analysis of protein interactions under truly physiological conditions with real medical devices [PDF]

open access: yes, 2012
PhDProtein adsorption under physiological conditions was recognised to be the key step in the modulation of biological responses between materials and an osseous environment.
Mafina, Marc-Krystelle
core   +2 more sources

Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2022
Aquaporin-4 (AQP4) is the predominant water channel in the brain; it is enriched in astrocytic foot processes abutting vessels where it is anchored through an interaction with the dystrophin-associated protein (DAP) complex.
Nadia Skauli   +5 more
doaj   +1 more source

Bone morphogenetic proteins: Signaling periodontal bone regeneration and repair

open access: yesJournal of Pharmacy and Bioallied Sciences, 2016
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal ...
G Sai Anusuya   +5 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Glypicans Dally and Dally-like control injury-induced allodynia in

open access: yesMolecular Pain, 2019
Over 100 million people are challenged by the effects of chronic pain in the United States alone. This burden also impacts the U.S. economy; 600 billion dollars annually is spent on medical care, medications, and lost productivity in the workplace ...
Courtney L Brann   +2 more
doaj   +1 more source

Investigation of the Role of BMP2 and -4 in ASD, VSD and Complex Congenital Heart Disease

open access: yesDiagnostics, 2023
Congenital heart malformations (CHMs) make up between 2 and 3% of annual human births. Bone morphogenetic proteins (BMPs) signalling is required for chamber myocardium development.
Dimitrios Bobos   +5 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

High-Density Lipoproteins from Coronary Artery Disease and Aortic Valve Stenosis Patients Differentially Regulate Gene Expression in a Model of Cardiac Adipocytes

open access: yesCells
Previous reports have described a statistical association between high-density lipoproteins (HDL) subclasses and the expression of genes coding for pro-calcifying proteins in the epicardial adipose tissue of patients with coronary artery disease (CAD ...
María Luna-Luna   +12 more
doaj   +1 more source

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