Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development [PDF]
Background: Adrenal chromaffin cells and sympathetic neurons both originate from the neural crest, yet signals that trigger chromaffin development remain elusive.
Huber, Katrin +39 more
core +1 more source
Background/purpose: Bone morphogenetic protein-4 (BMP-4) plays an important role during embryonic development of tooth and bone. Studies have found that the BMP-4 polymorphism rs17563 (T>C) influenced bone loss around implants; however, its impact on ...
Shin-Chie Wu +5 more
doaj +1 more source
Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core +1 more source
The role of bone morphogenetic proteins 2 and 4 in mouse dentinogenesis [PDF]
The bone morphogenetic proteins (BMPs) play crucial roles in tooth development. However, several BMPs retain expression in the dentin of the fully patterned and differentiated tooth. We hypothesized that BMP signaling therefore plays a role in the function of the differentiated odontoblast, the job of which is to lay down and mineralize the dentin ...
Priyam, Jani +5 more
openaire +2 more sources
Osteo allogenic morphogenetic protein (OsteoAMP) is an allogenic morphogenetic protein derived from bone allograft through a novel tissue processing technique.
Gabriel Grisham +4 more
doaj +1 more source
Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk +5 more
core +1 more source
Bone morphogenetic protein 4 (BMP4) has been reported to regulate adipose development, but its role in preadipocyte proliferation has not been explored in vitro.
Hongyan Chen +7 more
doaj +1 more source
BMP4 Induces Cardiomyocyte Hypertrophy Through the Activation of ERK 1/2 Signaling Pathway in H9c2 Cells [PDF]
Bone morphogenetic protein-4 (BMP4) is a member of the bone morphogenetic protein family which plays an important role in bone formation, inflammation and cardiac hypertrophy.
Yu Yuan +5 more
doaj +2 more sources
Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells [PDF]
As adult cartilage has very limited potential to regenerate, cartilage repair is challenging. Available treatments have several disadvantages, including formation of fibrocartilage instead of hyaline-like cartilage, as well as eventual ossification of the newly formed tissue.
Miljkovic, N.D. +2 more
openaire +2 more sources
RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis [PDF]
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell differentiation and axon guidance.
Coutinho, L. +9 more
core +1 more source

