The mechanisms of lncBMP4 mediating BMP4 promoter activity to regulate the proliferation of dermal papilla cells in Hu sheep [PDF]
Animal BioscienceObjective Dermal papilla cells (DPCs) are the regulatory center of hair follicle (HF) development, and their proliferation is critical in HF growth studies. Long non-coding RNAs (lncRNAs) have been demonstrated to regulate the HF growth cycle. This study
Hui Zhou +6 more
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The Role of BMP4 in Adipose-Derived Stem Cell Differentiation: A Minireview
Frontiers in Cell and Developmental Biology, 2022 Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor beta (TGF-β) superfamily of cytokines responsible for stem cells’ commitment to differentiation, proliferation, and maturation.
Taty Anna Kamarudin +2 more
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BMP4 Cross-Talks With Estrogen/ERα Signaling to Regulate Adiposity and Glucose Metabolism in Females
EBioMedicine, 2016 Similar to estrogens, bone morphogenetic protein 4 (BMP4) promotes the accumulation of more metabolically active subcutaneous fat and reduction of visceral fat.
Liang Guo, Qiqun Tang, Xi Li
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Synapse Elimination Triggered by BMP4 Exocytosis and Presynaptic BMP Receptor Activation
Cell Reports, 2018 In vitro screening of signaling molecules involved in neural circuit formation has identified a large number of synaptogenic proteins. However, factors that drive synapse elimination remain elusive. Here, we report that bone morphogenetic protein 4 (BMP4)
Shigeo Okabe
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Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells [PDF]
BioImpacts, 2023 Introduction: Human endometrial mesenchymal stem cells (hEnMSCs) are a rich source of mesenchymal stem cells (MSCs) with multi-lineage differentiation potential, making them an intriguing tool in regenerative medicine, particularly for the treatment of ...
Diba Ghasemi +10 more
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Small molecule-induced destabilization of β-catenin and RAS is the ideal strategies for suppressing colorectal cancer [PDF]
Organoid, 2023 Background Mutations of adenomatous polyposis coli (APC) and KRAS play essential roles in the development of colorectal cancer (CRC) by forming an abnormal colon morphology.
Yonghyo Kim +3 more
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Expression of BMP-4 in dentigerous cyst and ameloblastoma: Is it a differentiation measure?
European Oral Research, 2022 Purpose: This study aimed to determine the expression of Bone Morphogenic Protein-4 (BMP 4) in dentigerous cyst (DC), unicystic-ameloblastoma (UA), and Multicystic-ameloblastoma (MA), and assess whether this marker can be a differentiation measure ...
Soudabeh Sargolzaei +2 more
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BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo
Biology Open, 2021 Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development.
Sapna Chhabra, Aryeh Warmflash
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Effects of Treatment with Bone Morphogenetic Protein 4 and Co-culture on Expression of Piwil2 Gene in Mouse Differentiated Embryonic Stem Cells [PDF]
International Journal of Fertility and Sterility, 2009 Background Specific growth factors and feeder layers seem to have important roles in in vitro embryonic stem cells (ESCs) differentiation. In this study,the effects of bone morphogenetic protein 4 (BMP4) and mouse embryonic fibroblasts (MEFs) co-culture ...
Zohreh Makoolati +2 more
doaj +1 more source
Cell Journal, 2020 Objective: Bone morphogenetic protein 4 (BMP4) and basic fibroblast growth factor (bFGF) play important roles in embryonic heart development.
Sanaz Hasani +3 more
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