Results 41 to 50 of about 32,745 (240)
, 2012 Because periodontal ligament PDL cells are reported to contain progenitor or stem cell populations, they are considered a beneficial cell source for clinical periodontal regeneration.
秘心吾;傅鍔;周綠蘋;林俊彬 +1 more
core +1 more source
, 2011 (A) AGM cells (10·5 dpc) were analysed by flow cytometry (CyAn ADP Flow Cytometer) for expression of CD34, c-Kit, Flk1 and CD45 to identify subpopulations. Representative results are shown.
Joanna C Sinclair (91388) +3 more
core +1 more source
FEBS Open Bio, 2019 Bone morphogenetic protein 4 (BMP4) has been reported to regulate adipose development, but its role in preadipocyte proliferation has not been explored in vitro.
Hongyan Chen +7 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
A new function of BMP4: dual role for BMP4 in regulation ofSonic hedgehogexpression in the mouse tooth germ [PDF]
Development, 2000 ABSTRACTThe murine tooth development is governed by sequential and reciprocal epithelial-mesenchymal interactions. Multiple signaling molecules are expressed in the developing tooth germ and interact each other to mediate the inductive tissue interactions.
Y, Zhang +7 more
openaire +2 more sources
The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup [PDF]
, 2006 Background: Polarised gene expression is thought to lead to the graded distribution of signaling molecules providing a patterning mechanism across the embryonic eye.
Behesti, H, Holt, JKL, Sowden, JC
core
Interlinked signaling feedback loops and self-regulation during vertebrate limb development [PDF]
, 2009 Reliable organ and tissue morphogenesis seems to depend on self-regulatory mechanisms that are able to buffer spontaneous and/or genetic variations. While the analysis of the interactions of BMPs with their antagonists during gastrulation has provided ...
Bénazet, Jean-Denis
core +1 more source
Anales de la Facultad de MedicinaEn esta revisión examinaremos estudios sobre biología molecular que revolucionaron los conceptos actuales sobre la evolución animal, generando una nueva disciplina llamada Evo-Devo en inglés, o evolución y desarrollo molecular en castellano.
Edward M. De Robertis
doaj +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways [PDF]
The American Journal of Human Genetics, 2008 Developmental ocular malformations, including anophthalmia-microphthalmia (AM), are heterogeneous disorders with frequent sporadic or non-Mendelian inheritance. Recurrent interstitial deletions of 14q22-q23 have been associated with AM, sometimes with poly/syndactyly and hypopituitarism.
Bakrania, P. +20 more
openaire +3 more sources