Results 21 to 30 of about 75,633 (154)

A Role for Bone Morphogenetic Protein-4 in Adipocyte Development [PDF]

Cell Cycle, 2007
Obesity is characterized by increases in the number of mature adipocytes. Nascent adipocytes arise from mesenchymal stem cells (MSCs) by a multi-step process--MSCs are recruited to the adipocyte lineage forming determined preadipocytes, these committed progenitors proliferate, undergo growth arrest, and finally differentiate into mature adipocytes ...
Robert R, Bowers, M Daniel, Lane
openaire   +2 more sources

Bone Morphogenetic Protein 1 Prodomain Specifically Binds and Regulates Signaling by Bone Morphogenetic Proteins 2 and 4 [PDF]

Journal of Biological Chemistry, 2007
Highly purified fractions of bone extracts capable of inducing ectopic bone formation have been reported to contain peptides corresponding to the mature active regions of the TGF-beta-like bone morphogenetic proteins (BMPs) 2-7, and to the prodomain region of the metalloproteinase BMP1.
Reema, Jasuja, Gaoxiang, Ge, Nikolas G, Voss, Jamie, Lyman-Gingerich, Amanda M, Branam, Francisco J, Pelegri, Daniel S, Greenspan   +6 more
openaire   +2 more sources

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells [PDF]

Osteoarthritis and Cartilage, 2008
As adult cartilage has very limited potential to regenerate, cartilage repair is challenging. Available treatments have several disadvantages, including formation of fibrocartilage instead of hyaline-like cartilage, as well as eventual ossification of the newly formed tissue.
Miljkovic, N.D., Cooper, G.M., Marra, K.G.   +2 more
openaire   +2 more sources

Association of bone morphogenetic protein-4 gene polymorphism with periodontitis in a Taiwanese population

Journal of Dental Sciences, 2013
Background/purpose: Bone morphogenetic protein-4 (BMP-4) plays an important role during embryonic development of tooth and bone. Studies have found that the BMP-4 polymorphism rs17563 (T>C) influenced bone loss around implants; however, its impact on ...
Shin-Chie Wu, Earl Fu, Hsien-Chung Chiu, Fu-Gong Lin, E-Chin Shen, Cheng-Yang Chiang   +5 more
doaj   +1 more source

Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma

Neoplasia: An International Journal for Oncology Research, 2017
Human glioma, in particular, malignant forms such as glioblastoma exhibit dismal survival rates despite advances in treatment strategies. A population of glioma cells with stem-like features, glioma cancer stem-like cells (GCSCs), contribute to renewal ...
Guifa Xi, Benjamin Best, Barbara Mania-Farnell, Charles David James, Tadanori Tomita   +4 more
doaj   +1 more source

Analysis of remodeling and resorption rate of OsteoAMP bone allograft in LeFort midface reconstruction and malar augmentation

Oral and Maxillofacial Surgery Cases, 2022
Osteo allogenic morphogenetic protein (OsteoAMP) is an allogenic morphogenetic protein derived from bone allograft through a novel tissue processing technique.
Gabriel Grisham, Injamamul Niloy, Bradley Jones, Robert Shih, Richard Yim   +4 more
doaj   +1 more source

The role of bone morphogenetic proteins 2 and 4 in mouse dentinogenesis [PDF]

Archives of Oral Biology, 2018
The bone morphogenetic proteins (BMPs) play crucial roles in tooth development. However, several BMPs retain expression in the dentin of the fully patterned and differentiated tooth. We hypothesized that BMP signaling therefore plays a role in the function of the differentiated odontoblast, the job of which is to lay down and mineralize the dentin ...
Priyam, Jani, Chao, Liu, Hua, Zhang, Khaled, Younes, M Douglas, Benson, Chunlin, Qin   +5 more
openaire   +2 more sources

Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression

FEBS Open Bio, 2019
Bone morphogenetic protein 4 (BMP4) has been reported to regulate adipose development, but its role in preadipocyte proliferation has not been explored in vitro.
Hongyan Chen, Chang Liu, Chong Chen, Zhiyong Su, Jingting Shu, Ming Zhang, Hui Li, Bohan Cheng   +7 more
doaj   +1 more source

BMP4 Induces Cardiomyocyte Hypertrophy Through the Activation of ERK 1/2 Signaling Pathway in H9c2 Cells [PDF]

Brazilian Archives of Biology and Technology
Bone morphogenetic protein-4 (BMP4) is a member of the bone morphogenetic protein family which plays an important role in bone formation, inflammation and cardiac hypertrophy.
Yu Yuan, Yezheng Tao, Yongzhi Deng, Qunhui Ye, Bin Lin, Lin Wu   +5 more
doaj   +2 more sources